Contact urticaria to rubber gloves

Kleinhans, D

doi:10.1111/j.1600-0536.1984.tb00363.x

Cited by 49 publications

(7 citation statements)

References 3 publications

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“…Risk factors for the development of latex allergy appear to include atopy, dermatitis at sites of rubber contact, and direct skin or mucosal contact with rubber latex, e.g., latex glove wear or manufacture, or exposure to latex during multiple operations or repeated urinary catheterization (19)(20). Both types of allergy have been reported to coexist in some individuals with Type IV reactions preceding the development of Type I hypersensitivity (21,22). A case of Type I hypersensitivity to latex.…”

Section: Discussionmentioning

confidence: 99%

The problems of rubber hypersensitivity (Types I and IV) in chronic leg ulcer and stasis eczema patients

Gooptu

Powell

1999

Contact Dermatitis

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The prevalence of Type I and Type IV hypersensitivity to rubber allergens in patients with stasis eczema and/or venous leg ulcers over an 18‐month period was studied by prick and patch testing. Results from 109 patients were analysed. Positive patch tests were found in 71 patients (65%). Delayed‐type hypersensitivity to rubber chemicals was found in 17 patients (15.6%). However, only 1 patient who had additional risk factors showed Type I hypersensitivity to natural rubber latex. We therefore conclude that, although Type IV hypersensitivity to rubber chemicals is relatively common in our patients, Type I hypersensitivity to natural rubber latex remains rare.

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Section: Discussionmentioning

confidence: 99%

The problems of rubber hypersensitivity (Types I and IV) in chronic leg ulcer and stasis eczema patients

Gooptu

Powell

1999

Contact Dermatitis

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“…Natural and synthetic rubber polymers are rare as contact allergens, but natural rubber latex can cause contact urticaria, a condition which may be an immunological reaction which involves immediate wealing and flare (13)(14)(15)(16)(17)(18). In some cases, the skin reaction is followed by other symptoms, including eye irritation, rhinitis and asthma.…”

Section: Discussionmentioning

confidence: 99%

Dermatitis and urticaria from rubber and plastic gloves

1986

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The number and nature of allergic occupational glove dermatoses were analysed. 542 cases of allergic contact dermatosis were diagnosed during [1974][1975][1976][1977][1978][1979][1980][1981][1982][1983]. Amongst these, 68 (12.5%) were caused by rubber or plastic gloves. 2 patients had contact urticaria due to rubber gloves.Gloves were the main cause of occupational allergic rubber eczema, inducing 63 (58.3%) of 108 rubber eczema cases. 38 of them had positive reactions to rubber chemicals and glove material, 14 to glove material only, and II to rubber chemicals. 5 cases of allergic eczema from plastic gloves were diagnosed, all due to polyvinyl chloride (PVC). 2 cases of contact urticaria from natural rubber gloves were diagnosed by a provocation test. Epicutaneous testing with material of natural rubber gloves and rubber chemicals was negative.The present study shows that allergy to rubber gloves is usual, while allergy to plastic gloves is rare. Thus, plastic gloves should be used, when possible. Patch testing with protective gloves should always be used when patients develop prolonged hand dermatitis and where the possibility of glove eczema exists.

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“…Protein concentration of the non-dialysed and dialysed serum latex extracts was determined according to the method of Lowry et al [5] using bovine serum albumin as a standard.…”

Section: Protein Concentrationmentioning

confidence: 99%

“…Since 1979 several cases of contact urticaria attributed to rubber gloves have been described [2][3][4][5][6][7][8][9][10]. Although specific sensitivity to latex has already been demonstrated [10], the allergens involved in the patient's IgE-mediated response had not been identified.…”

Section: Introductionmentioning

confidence: 99%

Anaphylaxis produced by rubber glove contact. Case reports and immunological identification of the antigens involved

Morales

Basomba²,

Carreira

et al. 1989

Clin Experimental Allergy

145

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A study was carried out on six subjects suffering from anaphylactic reactions including asthma, rhinoconjunctivitis, contact urticaria and hypotension following contact with rubber gloves. All of them showed skin sensitivity and serum specific IgE to various preparations of natural latex, and not to other chemicals used in glove manufacturing. Immunoblotting techniques demonstrated that at least four soluble polypeptides from natural latex had the ability to bind specific human IgE. The results suggested that natural latex proteins present in rubber gloves can cause severe specific hypersensitivity reactions.

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Contact urticaria to rubber gloves

Cited by 49 publications

References 3 publications

The problems of rubber hypersensitivity (Types I and IV) in chronic leg ulcer and stasis eczema patients

The problems of rubber hypersensitivity (Types I and IV) in chronic leg ulcer and stasis eczema patients

Dermatitis and urticaria from rubber and plastic gloves

Anaphylaxis produced by rubber glove contact. Case reports and immunological identification of the antigens involved

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