On the morning of June 9, 2009, an explosion occurred at a manufacturing plant in Garner, North Carolina. By the end of the day, 68 injured patients had been evaluated at the 3 Level I trauma centers and 3 community hospitals in the Raleigh/Durham metro area (3 people who were buried in the structural collapse died at the scene). Approximately 300 employees were present at the time of the explosion, when natural gas being vented during the repair of a hot water heater ignited. The concussion from the explosion led to structural failure in multiple locations and breached additional natural gas, electrical, and ammonia lines that ran overhead in the 1-story concrete industrial plant. Intent is the major difference between this type of accident and a terrorist using an incendiary device to terrorize a targeted population. But while this disaster lacked intent, the response, rescue, and outcomes were improved as a result of bioterrorism preparedness. This article discusses how bioterrorism hospital preparedness planning, with an all-hazards approach, became the basis for coordinated burn surge disaster preparedness. This real-world disaster challenged a variety of systems, hospitals, and healthcare providers to work efficiently and effectively to manage multiple survivors. Burn-injured patients served as a focus for this work. We describe the response, rescue, and resuscitation provided by first responders and first receivers as well as efforts made to develop burn care capabilities and surge capacity. A t 11:27 a.m. on June 9, 2009, the first of many 911 calls began flooding the emergency communications center. The calls for help described an explosion at an industrial plant in Garner, North Carolina, a town in Wake County near Raleigh. Approximately 300 employees had reported for work that morning. By the end of the day, 3 were dead and 68 injured (another patient would succumb to his injuries months later).An investigation concluded that the explosion resulted from a gas leak. Once the gas leak found an ignition source, DOI: 10.1089DOI: 10. /bsp.2013 the ensuing conflagration and explosion sent a shock wave through the concrete building, causing exterior walls to collapse, crushing cars parked next to the building, and blowing large holes in the ceiling. As these walls and ceiling sections collapsed, they ripped open additional supply lines of gas and ammonia and exposed electrical lines in multiple sections of the building, culminating in a horrific and deadly scene.and Bioterrorism: Biodefense Strategy, Practice, and Science Volume 12, Number 1, 2014 ª Mary Ann Liebert, Inc.The subsequent investigation concluded there had been no purposeful intent, and terrorism was ruled out. Nevertheless, one method of terrorizing a population is to purposefully explode an incendiary device to injure, mutilate, and kill people and to destroy buildings and infrastructure. 1 While this disaster lacked purposeful intent, the response, rescue, and outcomes reflected many of the efforts of the past decade in which terrorism and b...