Contemporary management of lipoblastoma

Speer, Allison L.; Schofield, Deborah E.; Wang, Kasper S.; Shin, Cathy E.; Stein, James E.; Shaul, Donald B.; Mahour, G. Hossein; Ford, Henri R.

doi:10.1016/j.jpedsurg.2007.10.068

Cited by 54 publications

(83 citation statements)

References 18 publications

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“…1,4,5 Se han descrito casos en adultos; sin embargo, son infrecuentes. 1 Se presenta, con más frecuencia, en varones, como una masa palpable, móvil y no dolorosa, habitualmente, localizada en el tronco y las extremidades (axilas, hombros, codos, manos) y, con menos frecuencia, en la ingle y el cuello.…”

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“…5,6 La principal dificultad diagnóstica se presenta entre lipoblastoma y lipoma o liposarcoma, ya que, radiológicamente, son neoplasias muy similares, pero de pronóstico muy diferente.…”

Section: Discussionunclassified

“…El tiempo de seguimiento es controversial; se sugiere de uno a tres años. 5,7,8 La recidiva aumenta en el caso de lipoblastomatosis. Estos se presentan hasta 84 meses después de la resección, generalmente, dentro de los 2 primeros años de seguimiento, por lo que se recomienda una vigilancia posoperatoria constante de, al menos, 5 años: cada 2 meses durante el primer año, cada 6 durante el segundo y tercer año y luego de forma anual.…”

Section: Discussionunclassified

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Lipoblastoma retroperitoneal gigante. Caso clínico

Rosière

Falcioni

Navacchia

et al. 2018

Arch Argent Pediatr

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Presentación de casos clínicos RESUMENEl lipoblastoma forma parte de los tumores derivados del tejido adiposo. Es una neoplasia benigna que se puede presentar de forma localizada o difusa, que afecta a niños en la primera infancia y que, generalmente, se localiza en el tronco y las extremidades. Estos tumores son poco frecuentes en la edad pediátrica, pero cuando uno de ellos se presenta, constituye un desafío que se debe resolver rápidamente por el riesgo de malignidad que implican otras lesiones neoplásicas, de similares características. El diagnóstico preoperatorio es dificultoso, ya que los métodos por imágenes no aportan información específica que permita diferenciarlos de otros tumores, como los liposarcomas. El diagnóstico definitivo es anatomopalógico y, en casos dudosos, es necesaria la confirmación citogenética. Se presenta el caso de un niño de 14 meses de edad con diagnóstico de lipoblastoma de localización retroperitoneal de gran tamaño. Palabras clave: neoplasias retroperitoneales, lipoblastoma, pediatría.ABSTRACT Lipoblastoma is part of tumors derived from adipose tissue. It is a benign neoplasm that can be localized or diffuse, affecting children in early childhood and usually located in the trunk and extremities. These tumors are uncommon in the pediatric age, but when one of them is present, it is a challenge that we must resolve quickly due to the risk of malignancy that involves other similar neoplastic lesions. The preoperative diagnosis is difficult, because the imaging methods do not provide specific information that allows us to differentiate them from other tumors, such as liposarcomas. The definitive diagnosis is anatomopathological and, in doubtful cases, cytogenetic confirmation is necessary. We present the case of a 14-month-old boy with diagnosis of large sized lipoblastoma of retroperitoneal localization. Lipoblastoma retroperitoneal gigante. Caso clínico Giant retroperitoneal lipoblastoma. Case report INTRODUCCIÓNLos tumores adiposos se clasifican como b e n i g n o s : l i p o m a , l i p o m a h e t e r o t ó p i c o , lipomatosis, hibernoma y variantes de lipoma, como lipoblastoma y lipoblastomatosis (LBS); o malignos: liposarcoma, que es extremadamente raro en la infancia.

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“…5,6 La principal dificultad diagnóstica se presenta entre lipoblastoma y lipoma o liposarcoma, ya que, radiológicamente, son neoplasias muy similares, pero de pronóstico muy diferente.…”

Section: Discussionunclassified

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Lipoblastoma retroperitoneal gigante. Caso clínico

Rosière

Falcioni

Navacchia

et al. 2018

Arch Argent Pediatr

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“…In histologically borderline cases cytogenetics can be used as a diagnostic tool in differentiating lipoblastoma from myxoid or well-differentiated liposarcomas and other adipose tumors [10] . To our knowledge, only in 1 case of perineal lipoblastoma cytogenetic analysis was needed in order to establish the diagnosis, as shown in table 1 [5] .…”

Section: Discussionmentioning

confidence: 99%

A Case of Maturing Perineal Lipoblastoma in an Infant

Soutis¹,

Christopoulos-Geroulanos²,

Stefanaki

2009

Med Princ Pract

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Objective: To report the unusual occurrence of a perineal lipoblastoma presenting as a painless enlarging mass in an infant. Case Presentation and Intervention: A 7-month-old boy presented with a 6-month history of an asymptomatic progressively enlarging perineal mass. Imaging studies were unable to provide a diagnosis. Complete resection of the mass was achieved and there was no recurrence at 18-month follow-up. Histopathologic findings were consistent with a maturing perineal lipoblastoma. Conclusion: This case report serves as a reminder to physicians and especially pediatric surgeons to consider perineal lipoblastoma in the differential diagnosis of soft tissue perineal masses in infancy.

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“…This rare benign tumor of adipose tissue arises from embryonic white fat (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). Adipose tissue tumors compose 6% of all soft tissue tumors in children and lipomas account for the majority of these adipose tissue tumors.…”

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confidence: 99%

Lipoblastoma in the inguinal region of an infant: Review of the literature

Küçük¹,

Ateş²

2016

Ankara Üniversitesi Tıp Fakültesi Mecmuası

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Lipoblastoma, a rare benign adipose tumor is primarily seen under the age of five years. Common sites of this tumor are extremities and trunk. The most common symptom is usually painless, rapidly growing soft mass. The usual recommended treatment of both lipoblastoma and lipoblastomatosis is complete surgical excision with clean surgical margins without compromising function or damaging adjacent structures. The aim of this paper is to present a case of 13-month old female infant who presented with a mass in the inguinal region and was diagnosed as lipoblastoma following surgical excision of the mass.Key Words: adipose tissue neoplasm; infant; lipoblastoma Lipoblastom, primer olarak 5 yaş altında görülen seyrek bir adipoz doku tümörüdür. En sık yerleşim yerleri gövde ve ekstremitelerdir. En sık semptomu ağrısız hızlı büyüyen yumuşak dokudur. Lipoblastom ve lipoblastomatozisin önerilen olağan tedavisi, fonksiyon kaybına yol açmadan ve komşu yapılara zarar vermeden gerçekleştirilen temiz cerrahi sınırlı tam cerrahi eksizyondur. Bu çalışmanın amacı, inguinal bölgede kitle ile başvuran ve lipoblastoma olarak tanı alıp kitlesi cerrahi olarak çıkarılan 13 aylık kız çocuğunun sunulmasıdır.

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Contemporary management of lipoblastoma

Cited by 54 publications

References 18 publications

Lipoblastoma retroperitoneal gigante. Caso clínico

Lipoblastoma retroperitoneal gigante. Caso clínico

A Case of Maturing Perineal Lipoblastoma in an Infant

Lipoblastoma in the inguinal region of an infant: Review of the literature

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