This paper reviews the integration of green building practices and smart technologies in developing countries, focusing on the challenges and opportunities these regions face. While developed nations have advanced significantly in sustainability through green building certifications and smart systems, developing countries encounter barriers such as financial constraints, limited technical expertise, and insufficient policy frameworks. This research employs a systematic literature review to examine case studies from Africa, Southeast Asia, and Latin America, exploring how these regions can adapt sustainable practices to their unique socio-economic and environmental conditions. The findings reveal that despite significant challenges, green building and smart technologies offer long-term benefits, including improved energy efficiency, reduced operational costs, and enhanced quality of life. Successful adaptations, such as using locally sourced materials and implementing low-cost smart systems, demonstrate the feasibility of sustainable development even in regions with limited resources. Case studies from Nigeria, South Africa, and Kenya showcase promising examples where sustainable construction has been successfully integrated. This paper contributes to the existing body of knowledge by providing an in-depth analysis of the factors enabling or hindering the adoption of green building and smart technologies in developing nations. The research concludes that stronger governmental support, enhanced technical training, and broader awareness campaigns are essential to overcoming these barriers. Key recommendations include implementing financial incentives for developers, scaling successful green building projects, and fostering public-private partnerships to promote innovation. Additionally, the study calls for policy reforms that align with international sustainability goals while considering local challenges. In conclusion, the integration of green building practices and smart technologies presents a viable solution for sustainable urbanization in developing countries, offering a path toward environmental and economic resilience.