Content of Chemical Elements in Hair of Moscow Children: Relation to Illness (1995-2004)

Skalny, Anatoly V.; Skalnaya, Margarita G.; Demidov, V. A.; Grabeklis, Andrei R.; Berezkina, Elena; Lobanova, Yu.N.; Serebryansky, Eugeny P.

doi:10.19112/2413-6174-2016-17-1-10-18

Cited by 5 publications

(3 citation statements)

References 1 publication

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“…С.М. Кирова, построенные без противофильтрационных экранов в бывших старицах реки Илек, а также в пойме реки на аллювиальных четвертичных песчано-гравийных отложениях, имеющих высокую проницаемость 1 Известно, что бор является условно-эссенциальным микроэлементом [8]. Он играет важную роль в некоторых биологических процессах, демонстрирует различные плейотропные эффекты -от противовоспалительных и антиоксидантных до модуляции различных систем организма.…”

Section: коммунальная гигиенаunclassified

The Association between Hair Levels of Boron and Disease Incidence in the Population of a Boron Geochemical Province: A Cross-Sectional Study

Batyrova¹,

Umarova²,

Umarov³

et al. 2021

PH&LE

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Background: A stable natural and technogenic boron geochemical province characterized by high environmental levels of boron has formed in the Aktobe Region of West Kazakhstan. The main local source of boron is sludge collectors of the boric acid production of the now destroyed chemical plant, built without impervious screens in the former old channels of the Ilek River, as well as in the river floodplain on alluvial quaternary sand and gravel deposits with high permeability. The objective of the study was to map hair levels of boron in residents of the Aktobe Region and to establish their relationship with disease incidence of the adult population. Materials and methods: The study included 340 permanent residents of the Aktobe Region, Republic of Kazakhstan, aged 18–60. Hair boron levels were measured by inductively coupled plasma mass spectrometry using a Nexion 300D spectrometer (PerkinElmer Inc., USA) coupled with an ESI SC-2 DX4 sampler (Elemental Scientific Inc., USA). Mapping was performed using the QGIS cross-platform geographic information system (QGIS 3.18). Results: The map of the boron status of the study participants visually demonstrated the uneven distribution of hair boron concentrations in the inhabitants of the region. Hair levels of boron were significantly higher in men than in women (p = 0.000). We established a strong direct correlation between hair levels of boron and the incidence of congenital anomalies and chromosomal abnormalities (r = 0.886, p = 0.019), diseases of the genitourinary system (r = 0.829, p = 0.042), respiratory diseases (r = 0.943, p = 0.005), diseases of the digestive system (r = 0.878, p = 0.021), diseases of the blood, hematopoietic organs and the immune system (r = 0.880, p = 0.017). Conclusion: The mapping of hair levels of boron in the residents of the Aktobe Region of West Kazakhstan gave a visual demonstration of the uneven distribution of environmental pollution with boron in the study area. The revealed relationships between boron concentrations in hair tissue and disease incidence in the boric geochemical province confirm the assumption that the ecological features of the environment can affect the health of the population, which requires further in-depth research.

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Section: коммунальная гигиенаunclassified

The Association between Hair Levels of Boron and Disease Incidence in the Population of a Boron Geochemical Province: A Cross-Sectional Study

Batyrova¹,

Umarova²,

Umarov³

et al. 2021

PH&LE

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“…The human brain develops all his life (Figure 1). In the world literature, the influence of ID and IDA on the functioning of the human and animal organism, including on the nervous system is discussed [81,84].…”

Section: Iron Deficiency and Nervous Systemmentioning

confidence: 99%

“…More than 200 proteins of iron homeostasis cannot function without corresponding cofactors: derivatives of group B vitamins, copper ions, manganese, zinc, etc. [137,138]. For example, 9 copper-containing enzymes and 22 manganese-dependent proteins are involved in the homeostasis of iron.…”

Section: Deficiency Of Iron In Patients With Imbalance Of Micronutrientsmentioning

confidence: 99%

Neurocognitive Dysfunctions in Iron Deficiency Patients

Жуковская¹,

Karelin²,

Rumyantsev³

2019

Iron Deficiency Anemia

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In this chapter, the authors described the actuality of the investigations of neurocognitive dysfunctions in patients with iron deficiency. In infants, the incidence of iron deficiency is 73%; the probability of its transition to iron deficiency anemia is very high. The development of myelin at an early age reduces the production of myelin, and the formation of g-aminobutyric acid worsens the metabolism of dopamine in the striatal brain, which leads to slowing of motor function and behavioral problems in the child. Children with iron deficiency conditions are prone to developmental delays, reduced school performance, and behavioral disorders. In older adults, cognitive dysfunctions depend on complications of the vascular nature, complicated by comorbid iron deficiency. Concomitant pathology also influences iron homeostasis. The regulating mechanisms of iron deficiency, as the same cognitive deficiency, despite the age involve more than 200 proteins from iron homeostasis, appropriate cofactors: derivatives of vitamin B, copper, manganese, zinc ions, enzymes, cell growth factors, etc. All these partners could influence separately or together to the development of iron deficiency and a complication of it neurocognitive dysfunctions. The combination of iron deficiency anemia and iron deficiency with comorbid pathology often exacerbates cognitive problems and requires a weighted approach to the choice of therapeutic correction tactics.

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Heavy metals as criteria of health and ecological well-being of the urban environment

Stepanova

Fomina

Valeeva

et al. 2018

Journal of Trace Elements in Medicine and Biology

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Content of Chemical Elements in Hair of Moscow Children: Relation to Illness (1995-2004)

Cited by 5 publications

References 1 publication

The Association between Hair Levels of Boron and Disease Incidence in the Population of a Boron Geochemical Province: A Cross-Sectional Study

The Association between Hair Levels of Boron and Disease Incidence in the Population of a Boron Geochemical Province: A Cross-Sectional Study

Neurocognitive Dysfunctions in Iron Deficiency Patients

Heavy metals as criteria of health and ecological well-being of the urban environment

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