Content of Methylated Inositols in Familiar Edible Plants

Abstract

Familiar plants contain large amounts of inositols; soybean, white clover, red clover, bush clover, locust tree, wisteria, and kudzu of the legume family contain pinitol (3-O-methyl-chiro-inositol) at approximately 200-600 mg/100 g fresh weight (FW). The contents of pinitol in other plants were 260 mg/100 g FW for sticky mouse-ear, 275 mg/100 g FW for chickweed, and 332 mg/100 g FW for ginkgo. chiro-Inositol of 191 and 156 mg/100 g FW was also found in dandelion and Japanese mallotus, respectively. Ononitol (4-O-methyl-myo-inositol) of 166 mg/100 g FW was found in sticky mouse-ear. Furthermore, young leaves of ginkgo contained sequoyitol (5-O-methyl-myo-inositol) of 287 mg/100 g FW. Hydroxyl radical scavenging activities of the methylated inositols were higher than those of the original inositols. Effective uses of these familiar edible plants are expected to promote good health.

Inositol, neural tube closure and the prevention of neural tube defects

“…Myo‐ inositol in the nonphosphorylated form, typically available in vitamin supplements, does not have this property. Although less abundant, D‐ chiro‐ inositol is also obtained from dietary sources, principally in the methylated form 3‐ O‐methyl‐D‐chiro ‐inositol (pinitol) (Negishi et al, ).…”

New approach for fast identification of cyclitols by MALDI‐TOF mass spectrometry

“…Different strategies including column chromatography, liquid–liquid partitioning and solid phase extraction (SPE) have been used for isolation and purification of cyclitols . Among the most popular methods for separation and identification of cyclitols are chromatographic techniques.…”

“…7 Different strategies including column chromatography, liquidliquid partitioning and solid phase extraction (SPE) have been used for isolation and purification of cyclitols. [8][9][10] Among the most popular methods for separation and identification of cyclitols are chromatographic techniques. The most commonly used and convenient techniques are thin layer chromatography (TLC), high performance liquid chromatography (HPLC) with refractive index (RI) detector, lightscattering detector (ELSD) or with mass spectrometry (MS) detector, as well as gas chromatography (GC) combined with MS in different configurations.…”

NMR‐based approach reveals seasonal metabolic changes in mate (Ilex paraguariensis A. St.‐Hil.)

“…paraguariensis leaf extracts showed different signal intensities (Figure ). The identification of oleic acid, linoleic acid, linolenic acid, glucose, myo ‐inositol, and the purine alkaloids caffeine and theobromine was based on comparison of 2D NMR experiments recorded on these samples with published spectra data and using the method of addition by spiking the extract samples with authenticated standards (Table ). 1 H NMR spectra for all replicates of each season from mate leaf extracts can be found in the Figures S5 to S8.…”