Content of some phenolic acids and rutin in the leaves and roots of Symphytum officinale L.

Tahirovic, I; Rimpapa, Z.; Ćavar, Suzana; Huseinović, Samira; Muradic, S; Salihović, Mirsada; Sofić, E.

doi:10.1055/s-0030-1264591

Cited by 10 publications

(7 citation statements)

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“…In another report [12], extracts of comfrey root were rich in rosmarinic, caffeic, and salvianolic acids. The profile of comfrey root phenolic compounds has also been reported by Alkan et al [20], Neagu et al [21], Roman et al [9], Sowa et al [22] and Tahirovic et al [11]. In order to assess the S. officinale root as a potential source of different phytochemicals, it is important to determine a detailed chemical profile.…”

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confidence: 71%

“…For the rest of phenolic compounds, PLE using 85% ethanol at 63 • C was the most appropriate. Tahirovic et al [11] also identified caffeic acid in comfrey root macerates obtained by water in lower concentration as compared with other phenolic acids. The presence of caffeic acid in macerates (70% EtOH, seven days) was also confirmed by Roman et al [9].…”

Section: Comparison Of Extraction Techniquesmentioning

confidence: 98%

“…The extracts were rich in phenolic acids, flavonoids, and allantoin. Furthermore, the profile of comfrey root phenolic compounds has been reported based on HPLC-DAD and HPLC-ED [11,21,22]. In the study by Neagu et al [21], extraction of phytochemicals from comfrey root was carried out by maceration using 50% ethanol and 50% methanol.…”

Section: Comparison Of Extraction Techniquesmentioning

confidence: 99%

“…In the literature, few papers dealt with the extraction of polyphenols from comfrey root relying mostly on conventional solid/liquid extraction [8][9][10][11][12].…”

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confidence: 99%

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Comparative Assessment of Phytochemical Profiles of Comfrey (Symphytum officinale L.) Root Extracts Obtained by Different Extraction Techniques

Nastić

Borrás-Linares²,

Lozano-Sánchez

et al. 2020

Molecules

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In this work a comparative study on phytochemical profiles of comfrey root extracts obtained by different extraction approaches has been carried out. Chemical profiles of extracts obtained by supercritical fluid (SFE), pressurized liquid (PLE), and conventional solid/liquid extraction were compared and discussed. Phytochemical composition was assessed by high-performance liquid chromatography coupled with electrospray time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) identifying 39 compounds reported for the first time in comfrey root, mainly phenolic acids and fatty acids. The influence of different extraction parameters on phytochemical profiles of S. officinale root was investigated for all applied techniques. PLE and maceration, using alcohol-based solvents (aqueous methanol or ethanol), were shown to be more efficient in the recovery of more polar compounds. Greater numbers of phenolics were best extracted by PLE using 85% EtOH at 63 °C. The use of SFE and 100% acetone for 30 min enabled good recoveries of nonpolar compounds. SFE using 15% EtOH as a cosolvent at 150 bar produced the best recoveries of a significant number of fatty acids. The main compositional differences between extracts obtained by different extraction techniques were assigned to the solvent type. Hence, these results provided comprehensive approaches for treating comfrey root enriched in different phytochemicals, thereby enhancing its bioaccessibility.

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mentioning

confidence: 71%

Section: Comparison Of Extraction Techniquesmentioning

confidence: 98%

Section: Comparison Of Extraction Techniquesmentioning

confidence: 99%

“…In the literature, few papers dealt with the extraction of polyphenols from comfrey root relying mostly on conventional solid/liquid extraction [8][9][10][11][12].…”

mentioning

confidence: 99%

See 2 more Smart Citations

Comparative Assessment of Phytochemical Profiles of Comfrey (Symphytum officinale L.) Root Extracts Obtained by Different Extraction Techniques

Nastić

Borrás-Linares²,

Lozano-Sánchez

et al. 2020

Molecules

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“…Their aglycone quercetin was also detected in 40% of samples at concertations of 11.3 to 36.5 ng/L. Hyperoside is a typical component of Hypericum perforatum, quercetin from Quercus (oak) while rutin is synthesized by both plants (Afendi et al 2012) as well as by Symphytum o cinale (Tahirovic et al 2010). The detection of rutin at high concentration (190.9 ng/L), among avonoids, could be linked to the abundant presence of Symphytum x uplandicum.…”

Section: Flavonoidsmentioning

confidence: 95%

Occurrence of Emerging Contaminants of Plant Origin in River Waters from Vejle, Denmark

Nanusha¹,

Krauß²,

Soerensen³

et al. 2020

Preprint

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Background: A large number of chemicals are constantly introduced to surface water from anthropogenic and natural sources. So far, unlike anthropogenic pollutants, naturally occurring compounds are not included in environmental monitoring programs due to limited knowledge on their occurrence and effects in the environment. Since first studies suggest that natural compounds might contribute to mixture risks in aquatic ecosystems and for drinking water production, there is a need to increase empirical evidence on the occurrence of these compounds in aquatic systems. To this end, we performed target screening on 160 toxic secondary plant metabolites (PSMs), prioritized in silico for their likelihood of occurrence, persistence, toxicity and mobility in river waters, using liquid chromatography coupled to high resolution mass spectrometry (LC-HRMS). The samples were collected during rain events from three Danish rivers from an area covered by grassland, forest and agricultural crops. Results: In total, 27 targets belonging to different compound classes such as alkaloids, coumarins and flavonoids were detected, among them 12 compounds, which have not been reported in surface waters before. The most prominent compound class was the group of alkaloids with 41 % of the detected targets, many of them detected in more than 80 % of the samples. Individual compound concentrations were up to several hundred ng/L with the neurotoxic alkaloid coniine from poison hemlock and the flavonoid daidzein reaching highest maximum concentrations. Conclusions: The measured natural toxin concentrations are well within the range of those of synthetic environmental contaminants and need to be considered for the assessment of potential risks on aquatic organisms and drinking water production.

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SymphytumSpecies

2020

Secondary Metabolites of Medicinal Plants

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Content of some phenolic acids and rutin in the leaves and roots of Symphytum officinale L.

Cited by 10 publications

References 0 publications

Comparative Assessment of Phytochemical Profiles of Comfrey (Symphytum officinale L.) Root Extracts Obtained by Different Extraction Techniques

Comparative Assessment of Phytochemical Profiles of Comfrey (Symphytum officinale L.) Root Extracts Obtained by Different Extraction Techniques

Occurrence of Emerging Contaminants of Plant Origin in River Waters from Vejle, Denmark

SymphytumSpecies

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