Vignettes have been applied to train professionals in various fields, which has contributed to significant improvements in learning outcomes, ethical sensitivity and learners’ ethical decision-making. At the University of Nairobi’s Department of Educational Communication and Technology, most instructors have been slow to embrace experiential learning and inconsistent in applying vignettes to deliver business ethics lessons that emphasise ethical sensitivity in decision-making, with far reaching effects on the quality of graduates. This study responded to the information gap about the relationship between the use of vignettes and learners’ ethical sensitivity in decision-making at the University of Nairobi. Cross-sectional survey design guided the research process, and primary data were sourced in 2018 from 116 learners. Both quantitative and qualitative analysis techniques were applied. Key results show that learners who agreed strongly that the context of vignettes influences ethical sensitivity in decision-making were about 3.9 times as likely to make ethically sensitive decisions as colleagues who disagreed strongly. Those who agreed that the context of vignettes influences ethical sensitivity in decision-making had about 2.3 times the odds of making ethically sensitive decisions as colleagues who indicted strong disagreement. This means that the more the learners appreciated that the context of vignettes influences ethical sensitivity in decision-making, the higher the chances of them making ethically sensitive decisions, and vice-versa. This brings to the fore the need for instructors to consistently apply the context of vignettes to deliver business ethics lessons to improve learners’ ethical sensitivity and propensity to make ethical decisions. The study recommends that for practice, vignettes business contexts should be integrated in teacher training business studies ethics lessons.