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McElligott, Anthony

doi:10.3998/mpub.9690643

Cited by 10 publications

(3 citation statements)

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“…Furthermore, multiple stressors have been shown to increase NE release in the BNST, and blockade of postsynaptic α 1 -adrenergic receptors (α 1 -AR) in the BNST reduced circulating adrenocorticotropic hormone concentrations and blockade of α 1 -and βARs reduced anxiety-like behavior 14 . There appears to be a critical role of ARs in the BNST in the response to stress, as chronic restraint stress occludes the expression of α 1 -AR dependent plasticity 15 and multiple adrenergic receptors can drive release of corticotropin releasing factor within the BNST [15][16] .…”

mentioning

confidence: 99%

Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice

Schmidt¹,

Makhijani²,

Boyt³

et al. 2018

ACS Chem. Neurosci.

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Stress can drive adaptive changes to maintain survival during threatening stimuli. Chronic stress exposure, however, may result in pathological adaptations. A key neurotransmitter involved in stress signaling is norepinephrine. Previous studies show that stress elevates norepinephrine levels in the bed nucleus of the stria terminalis (BNST), a critical node regulating anxiety and upstream of stress responses. Here, we use mice expressing channelrhodopsin in norepinephrine neurons to selectively activate terminals in the BNST, and measure norepinephrine release with fast-scan cyclic voltammetry. Mice exposed to a single restraint session show an identical norepinephrine release profile compared to that of unexposed mice. Mice experiencing five days of restraint stress, however, show elevated norepinephrine release across multiple stimulation parameters, and reduced sensitivity to the α 2 -adrenergic receptor antagonist idazoxan. These data are the first to examine norepinephrine release in the BNST to tonic and phasic stimulation frequencies, and confirm that repeated stress alters autoreceptor sensitivity.

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confidence: 99%

Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice

Schmidt¹,

Makhijani²,

Boyt³

et al. 2018

ACS Chem. Neurosci.

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“…Sexual slurs in particular were aimed at destroying the self-image of puritans as 'pure, diligent, simple Christians'. 65 David Underdown has furthermore argued that the depiction of dominant women in civil war and Interregnum propaganda was another indicator of inversion, of the world being turned upside down. The portrayal of parliamentarians' wives as loose or sexually disordered was also common.…”

Section: Some Say Hees Proud Yett Foole and Clownementioning

confidence: 99%

‘Round-head Knaves’: the Ballad of Wrexham and the subversive political culture of Interregnum north-east Wales

Clavier

2017

Hist Res

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This article broadens ballad studies to encompass a regional perspective and significantly adds to the literature on Welsh royalism. It argues that the ballad author sought to destabilize the newly established parliamentarian government by attacking its members' honour, religion and personal morality. The article provides a contextualized and detailed textual analysis of a versified manuscript libel, a vitriolic and specific attack on the Wrexham committee of 1647. It considers it in the context of ballad and libel scholarship, Welsh political culture, and contemporary events, using a range of manuscript and printed sources to explain and analyse the ballad in depth.

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“…27 Charles, in fact, 'had enough sense to ensure that the vast majority of royalist propaganda of the early sixteen-forties avoided such extreme positions'. 28 Those around the king attempted to 'restyle' him as a constitutionalist monarch, respectful of the law and able to recognize the importance of parliament to the stability and happiness of the commonwealth. 29 Edward Hyde, the actual author of many of Charles I's public statements, encapsulated this royalist strategy when he told Lord Digby in November 1648 that 'whilst wee keepe ourselves upon the old foundacon of the established government, and the good knowne lawes, how weake soever wee are in power, wee shall be strong in reputacon'.…”

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confidence: 99%

Parliament, print and the politics of disinformation, 1642–3

White

2019

Historical Research

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This article explores the political uses of disinformation during the English civil war. It argues that forged and falsified publications formed part of a sophisticated propaganda strategy employed by the parliamentarian war party, aimed at discrediting Charles I during the first months of the conflict. It therefore offers an important corrective to traditional emphases on the anxieties that partisan print engendered. Furthermore, by showing that this strategy drew on both the practices and texts associated with early Stuart scribal opposition to Caroline rule, the article suggests an important link between pre‐war manuscript culture and the print practices of the sixteen‐forties.

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Contested City

Cited by 10 publications

References 0 publications

Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice

Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice

‘Round-head Knaves’: the Ballad of Wrexham and the subversive political culture of Interregnum north-east Wales

Parliament, print and the politics of disinformation, 1642–3

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