Contingent negative variation and evoked responses recorded by radio-telemetry in free-ranging subjects

Walter, W. Grey; Cooper, R.; Crow, H. J.; McCallum, W.C.; Warren, WJ; Aldridge, V.J.; Leeuwen, W. Storm van; Kamp, Annelies

doi:10.1016/0013-4694(67)90116-2

Cited by 46 publications

(10 citation statements)

References 12 publications

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“…4). A larger increase of the slow wave in the 9R− group may thus reflect stronger readiness (Walter et al. , 1967) whenever there is a sensory match between new and old auditory stimuli, resulting in a more efficient integration of the meaning of a new sound stimulus into the ongoing task context.…”

Section: Discussionmentioning

confidence: 99%

The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility

García-García

Barceló

Clemente

et al. 2010

Eur J of Neuroscience

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Cognitive flexibility, the ability to adapt goal-oriented behaviour in response to changing environmental demands, varies widely amongst individuals, yet its underlying neural mechanisms are not fully understood. Neuropharmacological and human clinical studies have suggested a critical role for striatal dopaminergic function mediated by the dopamine transporter (DAT). The present study aimed at revealing the role of the DAT in the individual brain response stereotypy underlying cognitive flexibility. A task-switching protocol was administered to a sample divided according to the presence or absence of the 9-repeat (9R) allele of the DAT1 polymorphism, while registering behavioural and electrophysiological novelty-P3 responses. The absence of the 9R (higher gene expression) is related to less striatal DA availability. Individuals lacking the 9R (9R-) showed specific response time (RT) increases for sensory change and task-set reconfiguration, as well as brain modulations not observed in participants with the 9R allele (9R+), suggesting that task performance of the former group depended on immediate local context. In contrast, individuals displaying high striatal DA showed larger RT costs than 9R- individuals to any sensory change, with no further increase for task-set reconfiguration, and a larger early positive brain response irrespective of the task condition, probably reflecting larger inhibition of any previous interference as well as stronger activation of the current task set. However, the polymorphic groups did not differ in their mean RTs in trials requiring task-set reconfiguration. This distinct stereotypy of cerebral responses reveals different patterns of cognitive control according to the DAT1 gene polymorphism.

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Section: Discussionmentioning

confidence: 99%

The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility

García-García

Barceló

Clemente

et al. 2010

Eur J of Neuroscience

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“…That is, expectancy was defined as the "subjective probability" or relative certainty that S 2 will follow 8! (Walter et al, 1967). Consequently, with S 2 omission there was presumed to be a decrease in "the probability of signal association as estimated by the subject [Walter, 1964b, p.…”

Section: Stimulus Withdrawalmentioning

confidence: 99%

Contingent negative variation (CNV) and psychological processes in man.

Tecce¹

1972

Psychological Bulletin

609

274

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“…Contingent Negative Variation (CNV) was for the first time described by Walter (1964a,b) and is characterised as a sustained potential change (involving mainly the frontal cortex) during which the surface of the brain becomes electro-negative by about 20 ȝV with respect to remote reference electrode or deeper structures (Walter et al, 1967). It is a slow negative deviation of EEG activity on the scalp which occurs in the interval between warning stimulus (S1) and imperative stimulus (S2) that is followed by a mental or motor response.…”

Section: Components Of Erpsmentioning

confidence: 99%

Event-related Potentials and Their Applications

et al. 2014

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Event-related potentials (ERPs) are characterised as brain voltage fluctuations associated in time with some physical or mental occurrence and represent a non-invasive technique reflecting activity of complex neuronal networks responsible for new stimuli detection and discriminative behaviour of individuals. ERPs are measured using electroencephalography and their applications became widespread since 1960s of the last century. This review brings introduction into the ERPs technique and characteristics of the individual ERPs components (particularly wave P300, Contingent Negative Variation, Mismatch Negativity and Bereitschaftspotential). In addition, it summarizes changes of ERPs associated with neurologic and psychiatric diseases and finally, it mentions possible use of this approach for purposes of experimental psychology.

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Contingent negative variation and evoked responses recorded by radio-telemetry in free-ranging subjects

Cited by 46 publications

References 12 publications

The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility

The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility

Contingent negative variation (CNV) and psychological processes in man.

Event-related Potentials and Their Applications

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