Continuing medical education

Zimmerman, Thomas F.; Kokemueller, Phillip

doi:10.1111/j.1365-2923.1988.tb00427.x

Cited by 2 publications

(3 citation statements)

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“…In many African cases, appropriate clinical management of snakebite patients requires identification of the distinctive clinical syndrome based on epidemiological, clinical, and laboratory data (e.g. 20WBCT), and consequently the syndromic approach is often recommended (15). Researchers and clinicians have sought to objectively quantify the severity of snakebite envenoming to minimize confusion due to the ambiguity of the definitions offered by current guidelines (197).…”

Section: Snakebite Diagnosis In Africamentioning

confidence: 99%

“…Researchers and clinicians have sought to objectively quantify the severity of snakebite envenoming to minimize confusion due to the ambiguity of the definitions offered by current guidelines (197). In Southern Africa, five main clinical syndromes of snakebite envenoming are recognized and often these guide diagnosis: Local pain and progressive swelling (cytotoxicity), progressive paralysis (neurotoxicity), incoagulable blood (hemotoxicity), moderate to marked local swelling (associated with otherwise neurotoxic bites), and mild to moderate swelling, with negligible or absent systemic effects (neurotoxicity and cytotoxicity) (15). However, with the syndromic approach, it is possible to misidentify snake species due to the similarity between symptoms that develop following envenoming from different types of snakes.…”

Section: Snakebite Diagnosis In Africamentioning

confidence: 99%

“…Once diagnosed, the mainstay treatment of severe envenoming is antivenom in combination with auxiliary treatment (7,14,15). Monovalent antivenoms can be used when the species of the offending snake is known, while polyvalent antivenoms are useful in cases where the snake species has not been identified.…”

Section: Introductionmentioning

confidence: 99%

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Snakebite Envenoming Diagnosis and Diagnostics

et al. 2021

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Snakebite envenoming is predominantly an occupational disease of the rural tropics, causing death or permanent disability to hundreds of thousands of victims annually. The diagnosis of snakebite envenoming is commonly based on a combination of patient history and a syndromic approach. However, the availability of auxiliary diagnostic tests at the disposal of the clinicians vary from country to country, and the level of experience within snakebite diagnosis and intervention may be quite different for clinicians from different hospitals. As such, achieving timely diagnosis, and thus treatment, is a challenge faced by treating personnel around the globe. For years, much effort has gone into developing novel diagnostics to support diagnosis of snakebite victims, especially in rural areas of the tropics. Gaining access to affordable and rapid diagnostics could potentially facilitate more favorable patient outcomes due to early and appropriate treatment. This review aims to highlight regional differences in epidemiology and clinical snakebite management on a global scale, including an overview of the past and ongoing research efforts within snakebite diagnostics. Finally, the review is rounded off with a discussion on design considerations and potential benefits of novel snakebite diagnostics.

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Section: Snakebite Diagnosis In Africamentioning

confidence: 99%

Section: Snakebite Diagnosis In Africamentioning

confidence: 99%