1995
DOI: 10.1159/000168863
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Continuous Ambulatory Peritoneal Dialysis Complicated by <i>Aureobasidium pullulans </i>Peritonitis

Abstract: We describe a case of peritonitis caused by Aureobasidium pullulans in a patient on continuous ambulatory peritoneal dialysis (CAPD). This dematiaceous fungus rarely causes infection in humans and to date has not been reported as an etiology of CAPD-associated peritonitis. The patient was managed successfully with peritoneal catheter removal and a prolonged course of intravenous amphotericin B, allowing resumption of CAPD. In vitro susceptibility testing confirmed sensitivity of this organism to amphotericin B. Show more

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Cited by 29 publications
(32 citation statements)
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“…Nosocomial infections caused by A. pullulans are rare and have been described only in some cases of peritonitis involving patients undergoing peritoneal dialysis and in one case of severe infection where the fungus was isolated from a splenic abscess (2,3,9,17). Even more uncommon are infections where A. pullulans can be isolated from blood cultures (5,10).…”
mentioning
confidence: 99%
“…Nosocomial infections caused by A. pullulans are rare and have been described only in some cases of peritonitis involving patients undergoing peritoneal dialysis and in one case of severe infection where the fungus was isolated from a splenic abscess (2,3,9,17). Even more uncommon are infections where A. pullulans can be isolated from blood cultures (5,10).…”
mentioning
confidence: 99%
“…A. pullulans strain NRRL Y-2331-1, which produces high yields of a nonpigmented form of pullulan, 9 was obtained from the United States Department of Agriculture (USDA). The growth media consisted of a complex nitrogen stock solution with sucrose as the carbon source, 5 containing (per 1 L of ultrapure water): 2.0 g of yeast extract, 0.5 g of (NH 4 ) 2 SO 4 , 1.0 g of NaCl, 0.2 g of MgSO 4 , 3.0 g of K 2 HPO 4 , 0.01 g of FeSO 4 , 0.01 g of MnSO 4 , 0.01 g of ZnSO 4 , and 50 g of sucrose. All ingredients, excluding ZnSO 4 , MnSO 4 , FeSO 4 , and MgSO 4 , were mixed and autoclaved for 45 min at 121°C.…”
Section: Methodsmentioning
confidence: 99%
“…The growth media consisted of a complex nitrogen stock solution with sucrose as the carbon source, 5 containing (per 1 L of ultrapure water): 2.0 g of yeast extract, 0.5 g of (NH 4 ) 2 SO 4 , 1.0 g of NaCl, 0.2 g of MgSO 4 , 3.0 g of K 2 HPO 4 , 0.01 g of FeSO 4 , 0.01 g of MnSO 4 , 0.01 g of ZnSO 4 , and 50 g of sucrose. All ingredients, excluding ZnSO 4 , MnSO 4 , FeSO 4 , and MgSO 4 , were mixed and autoclaved for 45 min at 121°C. For the remaining metals, stock solutions were prepared and sterile-filtered using 0.45-µm syringe filters, to avoid possible precipitation of the metals during autoclaving.…”
Section: Methodsmentioning
confidence: 99%
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“…Amphotericin-B alone or in combination with azoles has been tried with variable success. [3][4][5]8,9 Combination therapy is probably the treatment of choice. The duration of treatment is not certain, though most patients received antifungal treatment for 4-8 weeks.…”
mentioning
confidence: 99%