2020
DOI: 10.1038/s41598-020-77786-5
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Continuous and non-invasive thermography of mouse skin accurately describes core body temperature patterns, but not absolute core temperature

Abstract: Body temperature is an important physiological parameter in many studies of laboratory mice. Continuous assessment of body temperature has traditionally required surgical implantation of a telemeter, but this invasive procedure adversely impacts animal welfare. Near-infrared thermography provides a non-invasive alternative by continuously measuring the highest temperature on the outside of the body (Tskin), but the reliability of these recordings as a proxy for continuous core body temperature (Tcore) measurem… Show more

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Cited by 22 publications
(22 citation statements)
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“…As sleep and inactivity are often accompanied by body cooling ( 49 ), we examined if there was any change in skin temperature ( T skin ) using infrared thermography ( SI Appendix , Fig. S2 A ) as described in our previous study ( 50 ). T skin provides an estimate of changes in core body temperature over time ( 50 ).…”
Section: Resultsmentioning
confidence: 99%
“…As sleep and inactivity are often accompanied by body cooling ( 49 ), we examined if there was any change in skin temperature ( T skin ) using infrared thermography ( SI Appendix , Fig. S2 A ) as described in our previous study ( 50 ). T skin provides an estimate of changes in core body temperature over time ( 50 ).…”
Section: Resultsmentioning
confidence: 99%
“…To measure BST in a non-invasive way at high time resolution, we employed infrared camera-based thermal video imaging of living animals ( Fig 1A ). In previous reports, the highest body temperature of mice was defined as the BST [ 11 , 12 ]. However, we noticed that the highest values tended to vary depending on the posture of the animal.…”
Section: Resultsmentioning
confidence: 99%
“…device to record core body temperature, in addition to cranial EEG electrodes. Our thermal imaging cameras were fit-for-purpose in detecting relatively large changes in T surface such as those that occur during fasting-induced torpor, as previously published [ 52 , 53 ], but could also detect its minor fluctuations. We noted that the absolute values of T surface obtained in this study ( Figure 1 ) were variable between animals and consistently lower than previously reported temperature values recorded in small rodents from the brain or intraperitoneally placed thermistors.…”
Section: Methodsmentioning
confidence: 99%