Continuous cardiac baroreceptor measurement during tilt in healthy elderly subjects

Abstract

The values for cardiac BRS obtained using continuous time domain analysis agree well with those calculated using spectral methods and can be used to assess the dynamic changes in BRS to rapid perturbations in BP such as that occur with tilt.

Oral glucose tolerance test reduces arterial baroreflex sensitivity in older adults

“…Arterial baroreflex function was measured by the sequence method, which provides baroreflex sensitivity (in milliseconds per millimetre of Hg) and baroreflex effectiveness index (BEI) as percentage of baroreflex-mediated sequences. Both the baroreflex sensitivity (Johnson et al 2006;Youde et al 2002) and the BEI (Johansson et al 2005) have been used previously to examine baroreflex function in older adult subjects and are well validated against traditional measures such as the Oxford method (Bertinieri et al 1985;Parlow et al 1995).…”

Time-domain cross-correlation baroreflex sensitivity

“…Since the concept was proposed in 1969 [4], a number of methods have been developed for the assessment of BRS, some using a circulatory challenge such as injections of vasoconstrictor or vasodilator agents [4], neck suction [5] or a change from supine to standing [6,7], and some using spontaneous blood pressure and interval variability, studied in the time domain [8][9][10] or in the frequency domain [9,11] These various methods produce somewhat different numerical values [12], although results obtained on the same data set show acceptable correlation [3].…”

Influence of non-invasive measurements of arterial blood pressure in frequency and time-domain estimates of cardiac baroreflex sensitivity

“…Moreover, sequence analysis also has a much superior temporal resolution because sequences can occur, albeit spontaneously and randomly, at much shorter intervals. This property has led to the possibility of obtaining sequential estimates of BRS as demonstrated by Youde et al [23].…”