Continuous Epidural Infusion Analgesia with Buprenorphine and Bupivacaine for Postoperative Pain Relief: 1mlh-1 versus 2mlh-1 infusion rate.

Hirabayashi, Yoshihiro; Mitsuhata, H; Shimizu, R; Saitoh, K; Fukuda, Hirokazu

doi:10.2199/jjsca.15.673

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R Re El La At Ti Io On N B Be Et Tw We Ee En N P Ph Ha Ar Rm Ma Ac Co Ol Lo Og Gy Y a An Nd D C Cl Li In Ni Ic Ca Al L E Ef Ff F1

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2007

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“…While epidurally administered buprenorphine in a dose of 4 or 8 mg/kg provides postoperative analgesia that is as effective as that of morphine in a dose of 80 mg/kg, 24 a dose of 15 mg/h may be optimal for postoperative pain relief after lower abdominal surgery. 27 Buprenorphine is not as water-soluble as morphine. In a study of posthepatectomy patients, it was noted that buprenorphine injected at the thoracic level produced good and long-lasting pain relief, whereas buprenorphine injected at the lumbar level produced inadequate analgesia.…”

Section: R Re El La At Ti Io On N B Be Et Tw We Ee En N P Ph Ha Ar Rm Ma Ac Co Ol Lo Og Gy Y a An Nd D C Cl Li In Ni Ic Ca Al L E Ef Ff Fmentioning

confidence: 99%

Buprenorphine: A unique opioid with broad clinical applications

Vadivelu¹,

Hines²

2007

J of Opioid Management

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The analgesic potential of buprenorphine, a high-affinity partial m agonist, has been a subject of study for several decades. The drug is now widely recognized as being extremely effective in relieving perioperative pain, with little of the addictive potential or risk associated with pure m agonists. Studies have suggested that buprenorphine produces adequate analgesia via almost any route of administration, including transdermal and subcutaneous. It has also been used, with positive results, in the treatment of opioid addiction, and potential remains for research into other roles, e.g., as an anti-inflammatory agent or an antihyperalgesic medication.

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Section: R Re El La At Ti Io On N B Be Et Tw We Ee En N P Ph Ha Ar Rm Ma Ac Co Ol Lo Og Gy Y a An Nd D C Cl Li In Ni Ic Ca Al L E Ef Ff Fmentioning

confidence: 99%

Buprenorphine: A unique opioid with broad clinical applications

Vadivelu¹,

Hines²

2007

J of Opioid Management

View full text Add to dashboard Cite

show abstract

Continuous Epidural Infusion Analgesia with Buprenorphine and Bupivacaine for Postoperative Pain Relief: 1mlh-1 versus 2mlh-1 infusion rate.

Cited by 1 publication

References 8 publications

Buprenorphine: A unique opioid with broad clinical applications

Buprenorphine: A unique opioid with broad clinical applications

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