“…On the other hand, due to the lack of evidence in quantity of LA necessary to cover one dermatome after a bolus injection, De Cassai et al [49] performed a review of the medical literature. Indeed, after an injection of LA, the volume needed to cover one dermatome widely varies from 2.5 mL [1,26,8,2] to 6.6 mL [50,7], with a median value of 3.4 mL. Furthermore, the maximum number of dermatomes reached by a single bolus in ESP was of 9 dermatomes after a 30 mL bolus [33].…”