The covid-19 virus made its first appearance in late 2019. The virus originally arose in Wuhan and spread around the world as a result of people traveling. The SARS-CoV-2 virus has two traits that pushed the entire globe into a worldwide lockdown: exponential spread and high fatality rates. Health and economic crises, as well as social divisions, have placed the world in a precarious position. Unprecedented pressure on the health-care system highlighted several flaws not only in this business but also in many other industries, posing a new set of dif-faculties for researchers and scientists. An important step to attend in short time period to end the pandemic is vaccination. The vaccines had been clinically evaluated and authorized, bringing us to the immunization stage. In this situation, safety, security, transparency, and traceability are critical. In this paper, we propose a Block chain-based system to manage vaccine registration, storage, and distribution as a contribution to ensuring an effective immunization campaign.