Despite the increasing popularity of 3D printing, also known as additive manufacturing (AM), the technique has not developed beyond the realm of rapid prototyping. This confinement of the field can be attributed to the inherent flaws of layer-by-layer printing and, in particular, anisotropic mechanical properties that depend on print direction, visible by the staircasing surface finish effect. Continuous liquid interface production (CLIP) is an alternative approach to AM that capitalizes on the fundamental principle of oxygen-inhibited photopolymerization to generate a continual liquid interface of uncured resin between the growing part and the exposure window. This interface eliminates the necessity of an iterative layer-by-layer process, allowing for continuous production. Herein we report the advantages of continuous production, specifically the fabrication of layerless parts. These advantages enable the fabrication of large overhangs without the use of supports, reduction of the staircasing effect without compromising fabrication time, and isotropic mechanical properties. Combined, these advantages result in multiple indicators of layerless and monolithic fabrication using CLIP technology.stereolithogaphy | continuous liquid interface production | 3D printing | additive manufacturing | isotropic properties Additive manufacturing (AM), or 3D printing, is a growing field that employs the selective layering of material to build a part, which has distinct advantages compared with subtractive manufacturing (1). The benefits of additive over subtractive manufacturing are numerous and include unlimited design space, freedom of complex geometries, and reduction of waste by-products (2). Significant advancements were made to AM in the 1980s with the development of the stereolithography (SL) apparatus, a platform that uses the exposure of a rastering UV laser to selectively solidify a resin through a photopolymerization process in a top-down manner (3). The method has since been modified to solidify in a bottom-up process through the use of a digital light projection (DLP) chip that eliminates the rastering laser. The process of bottomup SL begins with a computer-aided design (CAD) file that is then converted into a series of 2D renderings using a method called "slicing" (Fig. 1A). The original object is then reconstructed in a layer-by-layer manner by reproducing these 2D renderings, one slice at a time. This process is done iteratively whereby a photoactive resin is selectively exposed to UV light through a transparent substrate, allowing for selective photopolymerization corresponding to a specific slice shape (4). Once the slice has been exposed, a series of mechanical steps of separation, recoating, and repositioning follow (Fig. 1B) to allow for subsequent exposure.The polymeric materials used in the SL process are known to have intrinsic properties that are a function of the chemical structure, molecular weight, and topology (3). Printed part properties differ from intrinsic polymeric properties because they a...