Continuous Peripheral Nerve Blockade for Inpatient and Outpatient Postoperative Analgesia in Children

Ganesh, Arjunan; Rose, John B.; Wells, Lawrence; Ganley, Theodore J.; Gurnaney, Harshad; Maxwell, Lynne G.; DiMaggio, Theresa; Milovcich, Karen; Scollon, Maureen; Feldman, Jeffrey M.; Cucchiaro, Giovanni

doi:10.1213/01.ane.0000284670.17412.b6

Cited by 104 publications

(85 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Postoperative analgesia was excellent. As demonstrated in other studies, [4][5][6]11 CPNB provided a high level of satisfaction in postoperative pain management in our pediatric patients. Nevertheless, we did not compare CPNB with other methods of postoperative analgesia.…”

Section: Quality Of Postoperative Analgesiasupporting

confidence: 82%

“…The incidence of PONV in our trial is similar to the results noted by Ganesh et al (14%). 6 The results of these two studies are lower than those of continuous pediatric epidural analgesia trials, which reported an incidence of PONV from 22 to 40%. [22][23][24] The authors claimed that nausea and vomiting were related to epidural opioid use.…”

Section: Adverse Eventsmentioning

confidence: 74%

“…These results are similar to those reported for adult and pediatric orthopedic patients receiving CPNB in the postoperative period. 6,7,17 In a similar study, Ganesh et al noted that 56% of children required an opioid within the first 8 hr after surgery. These results are higher than those reported in adults.…”

Section: Quality Of Postoperative Analgesiamentioning

confidence: 91%

“…In a limited number of patients, continuous peripheral nerve block (CPNB) has been reported to allow complete and prolonged postoperative pain relief in children. [4][5][6] CPNBs are associated with fewer side effects after lower limb surgery in children compared with continuous epidural blocks. 5 However, only one trial has been published with a high number of pediatric cases.…”

Section: Résumémentioning

confidence: 99%

“…5 However, only one trial has been published with a high number of pediatric cases. 6 Moreover, it has recently been reported that CPNB carries a low rate of complications in adult orthopedic patients, and major neurological and infectious adverse events are rare. 7,8 The incidence of these complications in children is unknown.…”

Section: Résumémentioning

confidence: 99%

See 4 more Smart Citations

Continuous peripheral nerve blocks for postoperative analgesia in children: feasibility and side effects in a cohort study of 339 catheters

Dadure

Bringuier

Raux³

et al. 2009

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Introduction Perioperative continuous peripheral nerve blocks (CPNB) are increasingly being used in children. Only one previous study has reported adverse events of CPNB in a high number of pediatric cases. We evaluated the indications, block efficacy, and adverse events related to CPNB in children. Methods All CPNBs that were performed in children for postoperative analgesia over a 5-year period at the Montpellier University Hospital in France were included in this study. The first bolus dose and the continuous doses of local anesthetic were not standardized. In the postoperative period, demographic data, quality of analgesia, amount of rescue analgesic medication, child/parent satisfaction, and adverse events were recorded in our Departmental Regional Anesthesia registry. Results A total of 339 catheters were evaluated in 292 children ASA physical status I to III. The median age was 8 yr (0.6-17 yr) and the median weight was 28 kg (7-116 kg). The main surgical indications were hip, femoral, or tibial osteotomies (44.5%) and club foot repair (27.4%). The local anesthetics used were either bupivacaine or ropivacaine. The mean volume of the local anesthetic bolus dose was 0.49 ± 0.16 mL Á kg -1 , and the mean regimen of local anesthetic continuous infusion was 0.11 ± 0.04 mL Á kg -1 Á hr -1 . The median duration of CPNB was 61.6 hr (range 0-264 hr). Pain relief, which was evaluated with the children at rest, was considered optimal in the majority of patients throughout the study period. The Children and Infants Postoperative Pain Scale (CHIPPS) was used in children age 0-6 yr and the Visual Analog Pain Scale (VAS) was used in children 7 yr and older. There were no major adverse events. There were 211 minor adverse events recorded in 153 CPNBs (45.1%). The most frequently reported complication (20.1%) involved mechanical problems with the catheter, followed by nausea and vomiting (14.7%). Conclusion CPNBs are indicated after orthopedic surgery in children. Our results demonstrate that CPNBs are feasible in the pediatric setting, and in skilled hands, they promote prolonged analgesia in the majority of patients without major adverse events. The most common minor adverse events are catheter-related mechanical problems and postoperative nausea and vomiting.

show abstract

Section: Quality Of Postoperative Analgesiasupporting

confidence: 82%