In the Oil & Gas Industry, large fleets of centrifugal pumps are used for different services working in diverse process conditions. More specifically in oil refineries, they have many characteristics in common since they are centrifugal machines that handle liquids using the same operating principle and because their design is highly standardized by API 610/ISO 13709 std for centrifugal pumps and API 682 std for sealing systems. As well, operating units and refining processes are well known and do not differ much regardless of where they are installed. Due to their criticality in the refining process, the reliability of these assets is of the utmost importance, being the MTBF (Mean Time Between Failures) one of the most used KPI (Key Performance Indicator) for evaluating it. Considering the characteristics indicated above, the possibility of predicting the MTBF of centrifugal pumps based on historical failure data, design features and expected operating conditions with Cox Proportional Hazards Model (PHM) is suggested.