Contraceptive failure with Copper T380A intrauterine device (IUD): A single tertiary center experience

Abstract

Objective:The objective of this study was to assess the risk factors of pregnancy with Copper (Cu)T380A IUD and pregnancy outcomes.Methods:A retrospective study evaluating the risk factors and pregnancy outcomes of 81 patients who conceived with CuT380A IUD in situ.Results:Four ectopic pregnancies and 77 intrauterine pregnancies were detected. Twenty-six pregnancies (33.76%, 26/77) were terminated according to maternal desire. Twenty-five patients (32.46%, 25/77) whose IUDs were removed constituted the Removed IUD Group, and the remaining 26 patients constituted IUD Left in situ Group. Term pregnancy rates (76% vs. 20.8%, p=0.002) were significantly higher in the Removed IUD Group compared with the IUD Left in situ Group. Abortion rates (16% vs. 53.84%, p=0.008) were detected significantly higher in the IUD Left in situ Group.Conclusion:The main result of our study was that pregnancy with CuT380A in situ is a significant risk factor for adverse perinatal outcome. Adjusting the scheduled follow-ups for checking the IUD seems to be important in order to prevent accidental pregnancy.

Clinical Opportunities for Continuous Biosensing and Closed-Loop Therapies

“…In this case, the continuous sensor serves as a monitor of released drug levels in the uterus. In addition, pressure sensors can be integrated into the device to ensure proper placement and to signal displacement during use [179]. Together, these sensors can be used to monitor proper device function and signal removal in the event of device failure.…”