Contrast-enhanced ultrasound features of focal pancreatic lesions in cats

Abstract

A large overlap in the ultrasound (US) features of focal pancreatic lesions (FPLs) in cats is reported. Furthermore, only a small number of studies describing the contrast-enhanced ultrasound (CEUS) features of FPLs in cats have been conducted today. The aim of this study is to describe the B-mode US and CEUS features of FPLs in cats. Ninety-eight cats cytologically diagnosed with FPL were included. The lesions were classified as adenocarcinoma (n = 40), lymphoma (n = 11), nodular hyperplasia (n = 17), other benign lesion (OBL) (n = 20), cyst (n = 4) or other malignant lesion (OML) (n = 6). Several qualitative and quantitative B-mode and CEUS features were described in each case. OMLs and cysts were not included in the statistical analysis. A decision tree to classify the lesions based on their B-mode and CEUS features was developed. The overall accuracy of the cross-validation of the decision tree was 0.74 (95% CI: 0.63–0.83). The developed decision tree had a very high sensitivity and specificity for nodular hyperplasia (1 and 0.94, respectively) as well as good sensitivity and specificity for both adenocarcinomas (0.85 and 0.77, respectively) and OBLs also (0.70 and 0.93, respectively). The algorithm was unable to detect any specific feature for classifying lymphomas, and almost all the lymphomas were classified as adenocarcinomas. The combination between CEUS and B-mode US is very accurate in the classification of some FPLs, especially nodular hyperplasia and adenocarcinomas. Cytopathology and or histopathology is still a fundamental step FPL diagnostic workflow.

Use of New Ultrasonography Methods for Detecting Neoplasms in Dogs and Cats: A Review

“…Pseudocyst-like lesions with intralesional vascularization were classified as adenocarcinomas. Adenocarcinomas and lymphomas presented large nodules with mixed echogenicity and hyper-or hypo-enhancement patterns [83]. The same study proved that contrast-enhanced ultrasound was sensitive and specific to differentiate nodular hyperplasia (100 and 94%), adenocarcinoma (85 and 77%) and other benign lesions (70 and 93%).…”

Візуальна Діагностика За Патології Підшлункової Залози У Котів

“…Зокрема, існують повідомлення про те, що у літніх котів протока панкреаса може в діаметрі сягати 3 мм; на рівні основного сосочка дванадцятипалої кишки протока підшлункової залози приєднується до загальної жовчної протоки [14]. Тіло підшлункової залози розташоване вентральніше за ворітну вену, між шлунком та поперечною ободової кишкою [15]. Ліву частку підшлункової залози візуалізували латерально від низхідної ободової кишки каудальніше дна шлунка, медіальніше селезінки і краніальніше краніального полюса лівої нирки, зважаючи на видимість протоки підшлункової залози (рис.…”