Contrast-Induced Nephropathy After Cardiac Catheterization: Culprits, Consequences and Predictors

Sedhai, Yub Raj; Golamari, Reshma; Timalsina, Santosh; Basnyat, Soney; Koirala, Ajay; Asija, Ankush; Choksi, Tatvam; Kushwah, Akanksha; Geovorgyan, David; Dar, Tawseef; Borikar, Madhura; Ahangar, Waseem; Alukal, Joseph; Zia, Subtain; Missri, José

doi:10.1016/j.amjms.2017.05.010

Cited by 17 publications

(15 citation statements)

References 19 publications

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“…Although hemoglobin was a predictor of CIN development in the univariate analysis, it lost its significance in the multivariate analysis. Heart failure has been reported to be a risk factor for CIN development in patients pwho underwent PCI 38 . Similarly, in this study the mean level of LVEF was signifincantly lower in the CIN group.…”

Section: Discussionmentioning

confidence: 99%

Impact of Geriatric Nutritional Index in Contrast-Induced Nephropathy Developed in Patients with Non-ST Segment Elevation Myocardial Infarction who Underwent Percutaneous Coronary Intervention

Küçükosmanoğlu

Yıldırım

Yavuz

et al. 2020

MMJ

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Objective: Geriatric nutritional risk index (GNRI) is a useful tool to determine the nutritional status of patients. Any study has not evaluated the impact of GNRI in development of contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI). We aimed to evaluate whether GNRI could predict CIN after PCI. Method: A total of 1116 patients with non-ST elevation myocardial infarction (non-STEMI) that underwent PCI were enrolled to the present study. The GNRI was calculated using a previously reported formula: GNRI=14.89 × albumin (g/dL) + 41.7 × body weight (kg)/ideal body weight (kg). CIN was defined as an increase in serum creatinine level of ≥0.5 mg/dL or ≥25% above baseline within 72 hours after the PCI procedure. The patients were categorized into two groups as CIN (+) and CIN (-). Results: The mean age of the CIN (+) group was significantly higher than the CIN (-) group (64.8±10.67 vs. 60.5±10.61 years; p<0.001). The mean values of height, weight, and body mass index were significanlty lower in CIN (+) group than CIN (-) group (p<0.001, for all). The mean of GNRI was significantly lower in the CIN (+) group than the CIN (-) group (101.4±8.7 vs. 112.1±12.9; p<0.001). Serum albumin level was significantly lower in the CIN (+) group (3.71±0.52 g/dL vs. 3.94±0.53 g/dL; p<0.001). Left ventricular ejection fraction (LVEF) was significantly lower in the CIN (+) group (50.7%±9.07 vs. 54.3%±7.20; p<0.001). Conclusion: In this study, GNRI, serum albumin level, BMI, and LVEF were independent predictors of CIN. Moreover, GNRI was better than both serum albumin level and BMI in predicting development of CIN.

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Section: Discussionmentioning

confidence: 99%

Impact of Geriatric Nutritional Index in Contrast-Induced Nephropathy Developed in Patients with Non-ST Segment Elevation Myocardial Infarction who Underwent Percutaneous Coronary Intervention

Küçükosmanoğlu

Yıldırım

Yavuz

et al. 2020

MMJ

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“…The appropriate evaluation of cardiac function is key to making the best treatment decisions for children with CHD [ 7 ]. Cardiac catheterization is considered to be the gold standard diagnostic method in many cases of CHD, but this method is invasive [ 8 , 9 ]. The combined use of cardiac tissue Doppler imaging (TDI) and the myocardial performance index (MPI) is a diagnostic modality that can quantify the indices of both systolic and diastolic ventricular function, and is a simple and non-invasive measurement method, which has good correlations with other invasive and noninvasive methods of diagnosing cardiac function [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

R-Wave Modified Tissue Doppler Imaging Myocardial Performance Index for the Assessment of Cardiac Function in Children with Congestive Heart Failure: A Feasibility Study

2018

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BackgroundThe aim of this study was to evaluate the feasibility of an R-wave modified tissue Doppler imaging (TDI) myocardial performance index (MPI), or MPI TDI-R, for the assessment of cardiac function in children with congestive heart failure (CHF).Material/MethodsForty children with CHF and 40 normal children were evaluated using the modified pediatric Ross heart failure grading system. TDI recorded the spectrum of diastolic function at the mitral valve annulus to measure the MPI. Twelve-lead electrocardiogram (ECG) measured the R-wave in the QRS complex, resulting in the modified MPI TDI-R. Correlation between the MPI TDI-R, other echocardiographic indices, and the Ross heart failure grades were analyzed, with reproducibility analysis.ResultsCompared with normal children, the MPI TDI and MPI TDI-R were significantly increased in the pediatric CHF group (P<0.01). The MPI TDI-R was significantly correlated with other indices of cardiac function and Ross grading for CHF in children (r=0.769). The MPI TDI-R showed good correlation with the findings of the MPI TDI, calculated by traditional methods. Receiver-operating characteristic (ROC) curve analysis showed that the MPI TDI-R had a sensitivity of 67.5%, and a specificity of 97.5%. The reproducibility of the MPI TDI-R was confirmed to be superior when compared with the non-modified MPI TDI.ConclusionsThis feasibility study showed that the modified MPI TDI-R, formed by combining the MPI TDI with synchronous surface ECG measurements, was simple to perform, reproducible, and provided a specific index for the assessment of cardiac function in children with CHF.

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“…The occurrence of prolonged kidney injury after coronary angiography is associated with an elevated long-term risk of mortality (4)(5) and renal replacement therapy. Contrast-induced nephropathy also prolongs the length of hospital stay (6).…”

Section: Introductionmentioning

confidence: 99%

Point-of-Care Capillary Blood Creatinine: A Prospective Study In Cardiology and Nephrology Outpatients

Vilaine¹,

Gabarre²,

Beauchet³

et al. 2020

Preprint

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Background: The radiological or interventional use of contrast medium exposes patients to a risk of contrast-induced nephropathy. Pre-existing kidney failure is a major risk factor. Point-of-care capillary (POC) blood creatinine tests are promising; their speed might help to optimize treatment decisions and patient care in these situations. Methods: The objective of the present study was to assess the ability of a new point of care capillary blood creatinine test (Stat Sensor X-press, Nova Biomedical Cooperation, Waltham, MA, USA) to diagnose kidney failure, relative to a standard lab-based plasma creatinine assay. A total of 113 patients 33 women (29.2%) were included. The capillary blood creatinine concentration was significantly correlated with the plasma creatinine concentration in both men (Pearson’s r [95% confidence interval (CI)] = 0.84 [0.75 – 0.89]; p<0.001) and women (Pearson’s r [95%CI] = 0.95 [0.89 – 0.97]; p<0.001). The test’s diagnostic performance was satisfactory, its sensitivity was 70% [35 – 93] in women and 78% [52 – 94] in men, and its specificity was 91% [72 – 99] in woman and 93% [84 – 98] in men. Conclusion: Rapid POC creatinine test is an easy-to-use, accurate tool for detecting kidney failure before a patient is exposed to procedures involving contrast medium.

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Contrast-Induced Nephropathy After Cardiac Catheterization: Culprits, Consequences and Predictors

Cited by 17 publications

References 19 publications

Impact of Geriatric Nutritional Index in Contrast-Induced Nephropathy Developed in Patients with Non-ST Segment Elevation Myocardial Infarction who Underwent Percutaneous Coronary Intervention

Impact of Geriatric Nutritional Index in Contrast-Induced Nephropathy Developed in Patients with Non-ST Segment Elevation Myocardial Infarction who Underwent Percutaneous Coronary Intervention

R-Wave Modified Tissue Doppler Imaging Myocardial Performance Index for the Assessment of Cardiac Function in Children with Congestive Heart Failure: A Feasibility Study

Point-of-Care Capillary Blood Creatinine: A Prospective Study In Cardiology and Nephrology Outpatients

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