Contrast medium extravasation injury: guidelines for prevention and management

Bellin, Marie‐France; Jakobsen, Jarl Å.; Tomassin, Isabelle; Thomsen, Henrik S.; Morcos, Sameh K.

doi:10.1007/s00330-002-1630-9

Cited by 130 publications

(81 citation statements)

References 37 publications

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“…Activated natural killer (NK) and T cells are the sources of IFNγ production. During early stages of infection, production of the cytokines interleukin (IL)-12 and IL-18 drives antigen-nonspecific IFNγ production by these lymphocyte populations [8, 9]. However, contact dependent mechanisms are also important for NK cell activation [10, 11].…”

Section: Introductionmentioning

confidence: 99%

Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections

2012

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The type I and II interferons (IFNs) play important roles in regulating immune responses during viral and bacterial infections and in the context of autoimmune and neoplastic diseases. These two IFN types bind to distinct cell surface receptors that are expressed by nearly all cells to trigger signal transduction events and elicit diverse cellular responses. In some cases, type I and II IFNs trigger similar cellular responses while in other cases the IFNs have unique or antagonistic effects on host cells. Negative regulators of IFN signaling also modulate cellular responses to the IFNs and play important roles in maintaining immunological homeostasis. In this review article, we provide an overview of how IFNs stimulate cellular responses. We discuss the disparate effects of type I and II IFNs on host resistance to certain intracellular bacterial infections and provide an overview of models that have been proposed to account for these disparate effects. Mechanisms of antagonistic cross talk between type I and II IFNs are also introduced.

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Section: Introductionmentioning

confidence: 99%

Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections

2012

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“…Cohan et al and Bellin et al cited undergoing chemotherapy as a risk factor for extravasation 10,11 . In the present study, 131 (70.80%) of the patients were undergoing or had undergone chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

Extravasation of iodinated contrast medium in cancer patients undergoing computed tomography

2018

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ObjectiveThe aim of this study was to evaluate the incidence of extravasation of iodinated contrast medium (ICM) at the site of intravenous injection in oncology patients submitted to computed tomography (CT).Materials and MethodsThis was a retrospective, descriptive, single-center study that evaluated all patients who underwent CT with ICM administration and presented ICM extravasation, at a cancer center, between January 2010 and December 2015.ResultsDuring the study period, we evaluated a total of 99,076 ICM injections and identified 199 cases of extravasation, the incidence rate therefore being 0.20%. Among the patients who presented extravasation, the mean age was 59.22 years and 60% were female. The extravasation was classified as mild in 94.10% of the patients and as moderate in 5.90%. There were no cases of severe extravasation in the sample.ConclusionThe incidence of ICM extravasation in cancer patients submitted to CT in the present study was similar to that reported for the general population, according to other studies in the literature. The vast majority of cases of extravasation were considered mild, and no severe cases were observed in the study sample.

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“…We suggest that more attention should be paid during sialography to prevent similar incidences and the operators should be informed about how much contrast agent should be infused as depicted in published data. Fortunately, most extravasations result in minimal swelling or erythema, with no long-term sequelae; however, severe skin necrosis and ulceration may occur (9). Conservative management with broad-spectrum antibiotics, short course of corticosteroids and analgesics are necessities for first-line management, which should be followed by definitive management of the respective pathological lesion once the acute problem is resolved.…”

Section: Discussionmentioning

confidence: 99%

Iatrogenic Submandibular Duct Rupture Complicating Sialography: A Case Report

Sharouny¹,

Omar²

2014

Iran Red Crescent Med J

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Introduction:Sialolithiasis is the most common disease of salivary glands. Sialography is particularly important for the assessment of the outflow tract and in diagnosing obstructive salivary gland lesions including calculi.Case Presentation:We report on a 38-year-old female with sialolithiasis whom had Wharton’s duct perforation, complicating the sialography. She was treated conservatively with a course of co-amoxiclav, oral prednisolone for three days and pain-killers. The patient was clinically well on follow-up reassessments at the end of the first week and three weeks post procedure.Conclusions:Perforation of salivary duct complicating the sialography is rare. Awareness of this potential complication and utilizing a good sialography technique need to be advocated amongst radiologists. Response to treatment by conservative management is preferred as illustrated in this case.

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Contrast medium extravasation injury: guidelines for prevention and management

Cited by 130 publications

References 37 publications

Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections

Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections

Extravasation of iodinated contrast medium in cancer patients undergoing computed tomography

Iatrogenic Submandibular Duct Rupture Complicating Sialography: A Case Report

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