The general objective of this research is to sense and monitor the main variables that affect biodigestion processes; temperature, hydrogen potential (pH), humidity, volume and pressure within the bioreactor, and correlate them with the production of biogas, through a real-time monitoring system. For the development of the system design, information was collected on the variables and factors that affect the biodigestion process. Subsequently, the instruments and integral elements of the monitoring and sensing system were selected, all these electronic devices for commercial use and mentioned below. An LM35 sensor for temperature measurement, an industrial analog type measuring electrode for pH measurement, an FC-28 for moisture measurement, an MQ2 electrochemical sensor for measurement of methane production, an HC-SR04 ultrasonic sensor for level measurement (related to the volume of the biodigester) and a piezoelectric sensor MPX2202DP case 344C-01 for pressure measurement. The values captured by the sensors will be displayed in real time in a Visual Studio application, and will be automatically saved in a database. The integration of the system was experimentally tested in a span of 12 days in the city of Hermosillo, Sonora, Mexico, where measurements were obtained for comparison with other authors.