2023
DOI: 10.1101/2023.11.22.568300
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Contribution of B-1 cells in the cytotoxicity of CD8 T lymphocytes in encephalitozoonosis

Cristina Gabriela Nascimento de Oliveira,
Elizabeth Cristina Perez,
Anuska Marcelino Alvares-Saraiva
et al.

Abstract: Encephalitozoon cuniculiis an opportunistic intracellular pathogen that establishes a balanced relationship with immunocompetent individuals depending on the activity of their CD8+T cells lymphocytes. However, lower resistance to experimental infection withE. cuniculiwas found in B-1 deficient mice (Xid), besides increased the number of CD8 T lymphocytes. Here, we evaluated the cytotoxic activity of CD8+T lymphocytes from Balb/c wild-type (WT) or Balb/c Xid mice (with B-1 cell deficiency) on the microbicidal a… Show more

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