“…Performing IOC means an increased operative time, which has been reported in the literature as 8, 10, 16, and 20 min respectively [9,58,67,68]. However, studies have indicated that despite the increased time in operative procedure and materials, routine IOC is cost-effective by reducing the severity of bile duct injury and the cost of treatment of patients with retained stones who did not receive IOC [56,61,69].…”