Little is knuwn about chidkood lead absorption in Souffi Africa. In this study acrosssectional analytic survey wascarried out to determine the blood lead levels and associated risk factors for inner-city, rfst-grade schoolchildren. Blood lead analyses, hematological and anthropometric measurements were conducted, and a pretested questionnaire was administered to parents to identify risk factors forlead exposure. In a detled environmental study, daily air and dust samples were collected over a period of 1 year from several sites in the study area, contemporaneously with the blood and questionnaire surveys. Spatial and temporal variations in atmospheric lead were determined.It was found that 13% ofmi,oed race children, but no whitechildren, had blood lead levels 2 25 ug/dL, the U.S. action klvel. Air lead levels averaged around 1 pg/n3, and dust lead levels ranged from 410 to3620 ppm. Environmental lead levels were significantly elevated near heavy trafic, where Environmental Protection Agency standards were exceeded mainly during winter months. Baselne osurewasof ae in i blood lead l s of childm attending sc in direct prximity to heavy taffic, where blood lead levels wereeevated iective ofother influening to. imary and secondary preventive measures are urgently needed in South Africa to reduce environmental lead exposure. At the time of the study, South Africa had one ofthe highest levels oflead in gasoline in the Western World, namely, 0.836 g/L.Although levels have subsequently been reduced, this is typical of the situation in many African countries today.