Contribution of left atrial volume and function in neurocardiogenic syncope

Başanalan, Fuat; Çoşkun, Fatma Yılmaz; Sucu, Murat; Altunbaş, Gökhan

doi:10.5152/eurjther.2017.24

Cited by 2 publications

(4 citation statements)

References 16 publications

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“…Previous research has demonstrated a drop in mxLAV in patients with VVS and HUTT+. 5,7 We, however, not only demonstrated reduced mxLAV in VVS but also showed differences in miLAV and pre-P LAV between VVS groups with HUTT+ and HUTT− and the control group.…”

Section: Discussionmentioning

confidence: 66%

“…Sucu et al 10 Başanalan et al 7 (2017) evaluated the LA ejection force, a marker derived from the mitral office area and the A wave, in patients with VVS and found that the force was lessened in patients with HUTT+ compared with those with HUTT−. They also reported that the LA ejection force was influenced by geometrical assumptions regarding Abbreviations: HUTT−, negative head-up tilt test; HUTT+, positive head-up tilt test; LA, left atrium; LAScd, left atrial longitudinal strain during the conduit phase; LASct, left atrial longitudinal strain during the contraction phase; LASr, left atrial longitudinal strain during the reservoir phase; pLASRcd, peak left atrial longitudinal strain rate during the conduit phase, pLASRct, peak left atrial longitudinal strain rate during the contraction phase; pLASRr, peak left atrial longitudinal strain rate during the reservoir phase; VVS, vasovagal syncope.…”

Section: Discussionmentioning

confidence: 99%

“…Başanalan et al 7 . (2017) evaluated the LA ejection force, a marker derived from the mitral office area and the A wave, in patients with VVS and found that the force was lessened in patients with HUTT+ compared with those with HUTT−.…”

Section: Discussionmentioning

confidence: 99%

“…The current evidence, however, suggests that changes in the volume or function of the heart chambers may be implicated in VVS recurrences. [5][6][7][8][9][10][11] The left atrium (LA) appears to play a part in VVS, probably as a consequence of decreased LA volumes, 5,7 LA hypocontractility during HUTT, 6,8 increased P-wave dispersions as an LA electrical activity index, 12 and lengthened atrial conduction times or intra-atrial delays as a marker of LA electromechanical function. 10 Evidence also indicates an association between syncope and atrial fibrillation.…”

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confidence: 99%

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Left atrial function evaluation by 2D speckle‐tracking echocardiography in patients with vasovagal syncope

Tajdini

Hosseinsabet

Tofighi

et al. 2023

Pacing Clinical Electrophis

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Objectives: Evidence indicates left atrial (LA) involvement in vasovagal syncope (VVS).The LA regulates left ventricular filling during the cardiac cycle. We aimed to assess LA function in patients with VVS by 2D speckle-tracking echocardiography.Methods: Sixty-nine consecutive patients with VVS were recruited. Based on the head-up tilt test (HUTT) results, the study population was divided into two groups: HUTT+ (n = 45) and HUTT− (n = 24). Fifty-one consecutive subjects were enrolled as the control group. LA myocardial deformation parameters were measured by 2D speckle-tracking echocardiography to evaluate LA function.Results: Maximal, minimal, and pre-P LA volumes were lower in patients with VVS. Strain and strain rate during reservoir, conduit, and contraction phases in VVS patients with HUTT+ or HUTT− were not statistically significantly different from those in the control group. Additionally, the volumetric parameters of LA function showed no difference in statistical significance between the three study groups.Conclusions: While LA phasic function was not different between the two groups of VVS patients with HUTT+ or HUTT− and the control group, LA size during the three LA phases was smaller in patients with VVS. K E Y W O R D Shead-up tilt test, left atrium, two-dimensional speckle-tracking echocardiography, vasovagal syncope Abbreviations: A, flow velocities of the mitral valve in late diastole; a′, velocity of mitral valve annulus at late diastole; D, flow velocities of the pulmonary vein in diastole; DT, deceleration time of the flow velocities of the mitral valve in early diastole; E, flow velocities of the mitral valve in early diastole; e′, velocity of mitral valve annulus at early diastole; HUTT, head-up tilt test; LA, left atrium; LAScd, left atrial longitudinal strain during the conduit phase; LASct, left atrial longitudinal strain during the contraction phase; LASr, left atrial longitudinal strain during the reservoir phase; LV, left ventricular; miLAV, minimal LA volume; mxLAV, maximal LA volume; pLASRcd, peak left atrial longitudinal strain rate during the conduit phase; pLASRct, peak left atrial longitudinal strain rate during the contraction phase; pLASRr, peak left atrial longitudinal strain rate during the reservoir phase; ppLAV, pre-P wave LA volume; S, flow velocities of the pulmonary vein in systole; s′, velocity of mitral valve annulus in systole; STE, speckle-tracking echocardiography; VASIS, Vasovagal Syncope International Study; VVS, vasovagal syncope.

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Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Left atrial function evaluation by 2D speckle‐tracking echocardiography in patients with vasovagal syncope

Tajdini

Hosseinsabet

Tofighi

et al. 2023

Pacing Clinical Electrophis

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Cardiac Geometry and Function in Patients with Reflex Syncope

Coseriu,

Schiop-Tentea,

Apetrei

et al. 2024

JCM

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Reflex syncope (RS) is the most prevalent form of syncope, yet its pathophysiology and clinical presentation are not well understood. Despite controversy, the ‘ventricular theory’ remains the most plausible hypothesis to explain RS in susceptible patients. Certain assumptions regarding the geometry and function of the heart are essential in supporting this theory. Given these considerations, the goal of this review was to try to integrate data on heart morphology and function in a phenotype of a patient susceptible to RS. Previous research suggests that a small left ventricle and atria, in addition to a normo- or hypercontractile myocardium, predispose to more syncopal events. These findings have been confirmed in different subsets of patients, including those with small heart and chronic fatigue syndrome, highlighting common pathophysiologic pathways in these subgroups of population. Heart geometry and function seem to play a role in different treatment strategies for RS patients, including the administration of medications, pacing, and possibly cardioneural ablation. In addition, parameters related to the geometry of the heart chambers and of the electrical activation of the heart seem to have predictive value for syncope recurrence. These parameters could be included in the future and improve the accuracy of predictive models for RS.

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Contribution of left atrial volume and function in neurocardiogenic syncope

Cited by 2 publications

References 16 publications

Left atrial function evaluation by 2D speckle‐tracking echocardiography in patients with vasovagal syncope

Left atrial function evaluation by 2D speckle‐tracking echocardiography in patients with vasovagal syncope

Cardiac Geometry and Function in Patients with Reflex Syncope

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