Contribution of molecular chiral mesoporous silica nanoparticles in delivering drugs with chiral recognition ability

Guo, Yingyu; Chen, Lin; Li, Xuan; Lin, Kai; Wu, Xuanjing; Wang, Ziqi; Yu, Dahai; Li, Jing

doi:10.1016/j.mseb.2022.115864

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…Subsequently, additional functional elements, such as Ca 2+ , -S-S-, and PEG, are introduced onto the surface of mesoporous silica to establish a delivery response to pH, GSH, temperature, etc. (see Table 1 ) [ 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ]. In recent years, enhancing therapeutic effects has led to a focus on constructing multifunctional drug delivery platforms.…”

Section: Applications Of Mesoporous Silicamentioning

confidence: 99%

Synthesis of Mesoporous Silica Using the Sol–Gel Approach: Adjusting Architecture and Composition for Novel Applications

Han,

Zhang,

Yang

2024

Nanomaterials

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The sol–gel chemistry of silica has long been used for manipulating the size, shape, and microstructure of mesoporous silica particles. This manipulation is performed in mild conditions through controlling the hydrolysis and condensation of silicon alkoxide. Compared to amorphous silica particles, the preparation of mesoporous silica, such as MCM-41, using the sol–gel approach offers several unique advantages in the fields of catalysis, medicament, and environment, due to its ordered mesoporous structure, high specific surface area, large pore volume, and easily functionalized surface. In this review, our primary focus is on the latest research related to the manipulation of mesoporous silica architectures using the sol–gel approach. We summarize various structures, including hollow, yolk-shell, multi-shelled hollow, Janus, nanotubular, and 2D membrane structures. Additionally, we survey sol–gel strategies involving the introduction of various functional elements onto the surface of mesoporous silica to enhance its performance. Furthermore, we outline the prospects and challenges associated with mesoporous silica featuring different structures and functions in promising applications, such as high-performance catalysis, biomedicine, wastewater treatment, and CO2 capture.

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