1989
DOI: 10.2337/diab.38.9.1082
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Contribution of Partial Pancreatectomy, Systemic Hormone Delivery, and Duct Obliteration to Glucose Regulation in Canine Pancreas: Importance in Pancreas Transplantation

Abstract: Our aim was to isolate and determine the contribution of partial pancreatectomy, systemic delivery of pancreatic hormones, and duct obliteration to glucose regulation after segmental pancreas transplantation in dogs. Fasting, postprandial, and intravenous glucose-stimulated glucose, insulin, glucagon, pancreatic polypeptide (PP), and cholecystokinin (CCK) and intravenous bombesin-stimulated PP levels were studied in beagles at three successive intervals in a crossover design. The first was 6 wk after partial (… Show more

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