2020
DOI: 10.1080/1028415x.2020.1815330
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Contribution of spathulenol to the anti-nociceptive effects of Psidium guineense

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Cited by 27 publications
(15 citation statements)
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“…Another major component found in the essential oil of the EflA specimen was the oxygenated sesquiterpene spathulenol (10.94%), which was also observed in the EflB specimen (1.2%). It is important to highlight that this substance has antioxidant, anti-inflammatory and antimicrobial activities [ 33 ], and insecticidal [ 34 ] and antinociceptive [ 35 ] activities. The monoterpene α-pinene (5.21%) is present in the EflA oil, but this substance was not identified in the EflB specimen.…”
Section: Resultsmentioning
confidence: 99%
“…Another major component found in the essential oil of the EflA specimen was the oxygenated sesquiterpene spathulenol (10.94%), which was also observed in the EflB specimen (1.2%). It is important to highlight that this substance has antioxidant, anti-inflammatory and antimicrobial activities [ 33 ], and insecticidal [ 34 ] and antinociceptive [ 35 ] activities. The monoterpene α-pinene (5.21%) is present in the EflA oil, but this substance was not identified in the EflB specimen.…”
Section: Resultsmentioning
confidence: 99%
“…Spathulenol 1Immunomodulator [32], anti-nociceptive [64], antimicrobial [65], alleviates cardiac fibrosis [66], antioxidant [33], antiproliferative, antimycobacterial [33], anti-inflammatory [33,67], antitumor [67].…”
Section: Secondary Metabolite Biological Activitiesmentioning
confidence: 99%
“…In addition, spathulenol was also demonstrated to be a significantly effective repellent against Aedes aegypti and Anopheles stephensi [ 43 ]. Furthermore, a recent in vivo study showed the acute and persistent antiedematogenic, antihyperalgesic, and anxiolytic activities of spathulenol [ 44 ].…”
Section: Discussionmentioning
confidence: 99%