“…Instances warranting an ophthalmologist's expertise for fundus examination might include, but are not limited to, suspected retinal detachment in the context of sudden onset floaters or flashes, evaluating for hypertensive or diabetic retinopathy in patients with uncontrolled glycemia, evaluating ocular manifestations in auto-immune diseases, examining for papilledema in scenarios of suspected elevated intracranial pressure or-as described in this paper-investigating potential ocular manifestations of systemic infec- Instances warranting an ophthalmologist's expertise for fundus examination might include, but are not limited to, suspected retinal detachment in the context of sudden onset floaters or flashes, evaluating for hypertensive or diabetic retinopathy in patients with uncontrolled glycemia, evaluating ocular manifestations in auto-immune diseases, examining for papilledema in scenarios of suspected elevated intracranial pressure or-as described in this paper-investigating potential ocular manifestations of systemic infections [1,19]. In the subsequent section, an overview of the principal ocular fundus findings in systemic infections, categorized according to etiological agents-bacterial, viral, fungal, and parasitic-will be described.…”