Contribution of the xenograft bone plate-screw system in lumbar transpedicular stabilization of dogs: anin-vitrostudy

Abstract

We performed biomechanical comparison of a xenograft bone plate-screw (XBPS) system for achieving cadaveric lumbar transpedicular stabilization (TS) in dogs. Twenty dogs' cadaveric L2-4 lumbar specimens were harvested and their muscles were removed, but the discs and ligaments were left intact. These specimens were separated to four groups: the L2-4 intact group as control (group I, n = 5), the L3 laminectomy and bilateral facetectomy group (LBF) (group II, n = 5), the LBF plus TS with metal plate-screw group (group III, n = 5) and the LBF plus TS with XBPS group (group IV, n = 5). Five kinds of biomechanical tests were applied to the specimens: flexion, extension, left-right bending and rotation. The averages of the 16 stiffness values were calculated and then these were statistically analyzed. The statistical results show that the XBPS system contributes spinal stability and this system can be a good choice for achieving TS.

Contribution of the xenograft bone plate-screw system in lumbar transpedicular stabilization: An in vivo study in dogs

“…[ 1 ] Therefore, to evaluate and reveal the fusion rate, between the vertebral segments, a considerable amount of experimental studies were reported. [ 4 7 8 9 10 12 13 14 ] Here, biomechanical and histological results of the study show the contributing role of XBPS in lumbar segments of the dogs with TS for stabilization.…”

“…The XBPSs were machined (Yunan Machine Tool Works, China) from cadaveric cattle tibia and sized as in the previous study. [ 10 ] Metal screws and plates had same size as in XBPS [ Figure 1 ]. Sterilization of the all equipment was made in autoclave, but XBPSs were boiled in 3% acide borique solution at 15 min for sterilization as described previously.…”

“…A universal testing machine (Hounsfield ® , UK) was used for biomechanical tests as reported in the previous study. [ 10 ] Six different types of loads were applied to specimens sequentially in the following order: Flexion, extension, left-right bending, rotation, and compression. To execute these motions, couple moments were applied on the specimens about different axes with the aim of a moment arm.…”

“…Data were collected in the same manner as in the previous study. [ 10 ] The load was applied monotonically, and the magnitude of loading is recorded for each 1 mm displacements. The test was interrupted at 16 mm displacement.…”

“…[ 4 7 8 9 ] We previously reported the in vitro biomechanical contribution of XBPS system in lumbar transpedicular stabilization (TS) of the dogs. [ 10 ] Here, it was aimed to demonstrate biomechanical and histopathological contribution of XBPS system in TS of the dogs.…”