Contribution of whole body FDG-PET to the detection of distant metastasis in pancreatic cancer

Abstract

These results suggest that FDG-PET and CT appear to have a complementary role in the detection of distant metastasis in patients with pancreatic cancer.

Stereotactic Body Radiation Therapy Boost in Locally Advanced Pancreatic Cancer

“…Restrictive inclusion criteria may be a limitation of this study; however, we think that rigorous staging workups are important to exclude patients with occult distant metastases to increase the survival of patients treated by RT. Use of PET/CT is still prone to false-negative results, especially in terms of detecting liver metastasis or peritoneal seeding (28)(29)(30). In the present study, many distant metastases (13 cases among 18 patients) were detected within 12 months of diagnosis, and it is possible that these 13 patients had synchronous undetectable metastatic disease at diagnosis.…”

Unusual Osteoblastic Metastases in the Spine Secondary to Adenocarcinoma of the Pancreas

“…It is recommended by HATFIELD et al to routinely use the bone scan to evaluate patients with carcinoma of the pancreas based on a detection rate of 6% (9). Besides, Positron Emission Tomography (PET) scan is useful to determine the primary tumours because the primary carcinomas in 30% of patients cannot be identified when bone metastases are first diagnosed (10).…”

Radioimmunoscintigraphy of pancreatic cancer in tumor-bearing athymic nude mice using 99mtechnetium-labeled anti-KL-6/MUC1 antibody

“…27 The principle of FDG-PET imaging is, again, not tumor-specifi c. Whether this method is superior to CT or MRI for the differential diagnosis of pancreatic cancer is a matter of discussion. [28][29][30][31] The present method of molecular imaging scintigraphy for pancreatic cancer detects KL-6, an extracellular epitope of the tumorspecifi c glycosylated protein MUC1. Therefore, use of this method for diagnosis in human subjects can be benefi cial for arriving at a precise diagnosis and deciding on a treatment program.…”