Control by Vaccination

Meulemans, G.

doi:10.1007/978-1-4613-1759-3_17

Cited by 38 publications

(36 citation statements)

References 71 publications

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“…Live vaccines are used in chickens for protection against NDV (Meulemans, 1988;Gallili & Ben-Nathan, 1998;Alexander & Jones, 2001;Cserep, 2001) and APV (Cook et al ., 1989;Williams et al ., 1991;Alexander & Jones, 2001). In some instances, other live vaccines are given concurrently with NDV vaccines (Gallili & Ben-Nathan, 1998).…”

Section: Introductionmentioning

confidence: 99%

Interaction between live avian pneumovirus and Newcastle disease virus vaccines in specific pathogen free chickens

Ganapathy

Cargill²,

Montiel³

et al. 2005

Avian Pathology

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One-day-old specific pathogen free White Leghorn chicks were vaccinated with live avian pneumovirus (APV) vaccine, live Newcastle disease virus (NDV) vaccine or both. At intervals up to 28 days after vaccination, distribution of the virus in the tissues was studied, together with humoral and mucosal antibody responses in lachrymal fluid and tracheal washes. APV vaccine was detected for almost twice as long in the dual vaccinates as in the single vaccinates. Higher numbers of isolations of ND virus vaccine were obtained from the dual rather than the single vaccinates at 7 days post-vaccination but the reverse occurred at 14 days. APV serum antibodies were significantly lower in the dual rather than the single vaccinates. However, there were similar levels of local APV-specific IgA in the lachrymal fluids of both single and dual APV vaccinates. NDV serum antibody titres in the dual vaccinates were significantly higher than in the singly NDVvaccinated chickens. It appears that simultaneous vaccination of chicks with live APV and NDV vaccines causes temporary suppression of APV vaccine proliferation and reduces humoral antibody responses to it, although the antibody response to NDV is enhanced.

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Section: Introductionmentioning

confidence: 99%

Interaction between live avian pneumovirus and Newcastle disease virus vaccines in specific pathogen free chickens

Ganapathy

Cargill²,

Montiel³

et al. 2005

Avian Pathology

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“…The Ulster strain has been periodically used as a vaccine strain outside the United States (1,25), while QV4 has been incorporated into poultry feed in developing countries as an oral vaccine due to its greater thermostability (4,14). All the lentogenic NDV field isolates analyzed during this study were most similar to the B1 strain and not to the Ulstertype vaccine.…”

Section: Discussionmentioning

confidence: 95%

“…The B1 isolate of NDV is the most widely used vaccine strain for Newcastle disease worldwide (1,25) and it was therefore Table 1. VOL. 39,2001 IMPROVEMENTS OF NDV DIAGNOSTICS 3175…”

Section: Discussionmentioning

confidence: 99%

“…It is currently a worldwide problem and all orders of birds have been reported to be capable of infection with NDV (1). Infectious virus may be transmitted by ingestion or inhalation, which is the basis of mass application vaccination procedures for poultry (25). Isolates of NDV may be categorized into three main pathotypes depending on severity of disease following chicken inoculation (1,2).…”

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confidence: 99%

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Use of a Heteroduplex Mobility Assay To Detect Differences in the Fusion Protein Cleavage Site Coding Sequence among Newcastle Disease Virus Isolates

et al. 2001

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Newcastle disease virus (NDV) is an economically important pathogen of poultry that may cause clinical disease that ranges from a mild respiratory syndrome to a virulent form with high mortality, depending on an isolate's pathotype. Infections with virulent NDV strains are required to be reported by member nations to the Office of International Epizootes (OIE). The primary determinant for virulence among NDV isolates is the presence or absence of dibasic amino acids in the fusion (F) protein cleavage activation site. Along with biological virulence determinations as the definitive tests, OIE accepts reporting of the F protein cleavage site sequence of NDV isolates as a virulence criterion. Nucleotide sequence data for many NDV isolates recently isolated from infected chickens and other avian species worldwide have been deposited in GenBank. Consequently, viral genomic information surrounding the F protein cleavage site coding sequence was used to develop a heteroduplex mobility assay (HMA) to aid in further identification of molecular markers as predictors of NDV virulence. Using common vaccine strains as a reference, we were able to distinguish virulent viruses among NDV isolates that correlated with phylogenetic analysis of the nucleotide sequence. This technique was also used to examine NDV isolates not previously characterized. We were able to distinguish vaccine-like viruses from other isolates potentially virulent for chickens. This technique will help improve international harmonization of veterinary biologics as set forth by the OIE and the Veterinary International Cooperation on Harmonization of Technical Requirements of Veterinary Medicinal Products. Ultimately, the HMA could be used for initial screening among a large number of isolates and rapid identification of potentially virulent NDV that continue to threaten commercial poultry worldwide.

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“…The NDV LaSota strain, a naturally occurring low-virulence NDV strain, has been routinely used as a live vaccine throughout the world (19). This vaccine strain induces strong immunity both locally and systemically and can be readily administered through drinking water supplies or by direct spray (20). The LaSota vaccine has been proven to be safe and stable, with no reports of virulence reversion or recombination with field strains.…”

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confidence: 99%

Newcastle Disease Virus (NDV) Recombinants Expressing Infectious Laryngotracheitis Virus (ILTV) Glycoproteins gB and gD Protect Chickens against ILTV and NDV Challenges

Zhao

Spatz

Zhang

et al. 2014

J Virol

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Infectious laryngotracheitis (ILT) is a highly contagious acute respiratory disease of chickens caused by infectious laryngotracheitis virus (ILTV). IMPORTANCEThis paper describes the development and evaluation of novel bivalent vaccines against chicken infectious laryngotracheitis (ILT) and Newcastle disease (ND), two of the most economically important infectious diseases of poultry. The current commercial ILT vaccines are either not safe or less effective. Therefore, there is a pressing need to develop safer and more efficacious ILT vaccines. In the present study, we generated Newcastle disease virus (NDV) recombinants expressing glycoproteins B (gB) and D (gD) of infectious laryngotracheitis virus (ILTV) using reverse genetics technology. These recombinant viruses were safe, stable, and immunogenic and replicated efficiently in birds. Vaccination of chickens with these recombinant viruses conferred complete protection against ILTV and NDV challenge. These novel bivalent vaccines can be mass administered via aerosol or drinking water to large chicken populations at low cost, which will have a direct impact on poultry health, fitness, and performance.

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Control by Vaccination

Cited by 38 publications

References 71 publications

Interaction between live avian pneumovirus and Newcastle disease virus vaccines in specific pathogen free chickens

Interaction between live avian pneumovirus and Newcastle disease virus vaccines in specific pathogen free chickens

Use of a Heteroduplex Mobility Assay To Detect Differences in the Fusion Protein Cleavage Site Coding Sequence among Newcastle Disease Virus Isolates

Newcastle Disease Virus (NDV) Recombinants Expressing Infectious Laryngotracheitis Virus (ILTV) Glycoproteins gB and gD Protect Chickens against ILTV and NDV Challenges

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