Control of a Community-Wide Outbreak of Hepatitis A by Mass Vaccination with Inactivated Hepatitis A Vaccine

Zamir, C; Rishpon, Shmuel; Zamir, Doron; Leventhal, Alex; Rimon, Nurit; Ben-Porath, E

doi:10.1007/s100960100461

Cited by 37 publications

(17 citation statements)

References 9 publications

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“…Any children had received immunoglobulin previously and only the vaccination was introduced to eradicate the infection. Zamir et al (2001) demonstrated that postexposure administration of immune globulin may diminish but not entirely arrest the transmission of HAV in community-wide outbreaks. The inactivated vaccine was demonstrated to be highly effective during an outbreak and when given in massive vaccination programs (Werzberger et al 1992, Innis et al 1994, McMahon et al 1996, Bonanni et al 1998.…”

Section: Discussionmentioning

confidence: 99%

Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil

Villar

Costa²,

Paula

et al. 2002

Mem. Inst. Oswaldo Cruz

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Section: Discussionmentioning

confidence: 99%

Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil

Villar

Costa²,

Paula

et al. 2002

Mem. Inst. Oswaldo Cruz

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“…Among them, perhaps the most important is change in socioeconomic and hygiene conditions. 39,40 In some Latin American regions, a decrease in cases in younger age groups has been noted over the last few years, with a shift in the seroprevalence curve of the infection to the adult age group. 41 This basically occurs as a result of the improvement in the populations sanitary and socioeconomic conditions.…”

Section: Impact Of Anti-hav Vaccinationmentioning

confidence: 99%

Prevenção das hepatites virais através de imunização

Ferreira¹,

Silveira²

2006

J. Pediatr. (Rio J.)

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Objective: To present an updated review and criticism of viral hepatitis A and B prevention by immunization. Summary of the findings: Viral hepatitis prevention is an enormous challenge to the public health systems of countries and the medical and scientific communities. Hepatitis viruses produce important morbimortality in the world, causing acute and chronic hepatic disease. There are highly efficient vaccines available on the market to prevent new infections by the A and B viruses. However, A and B viruses continue to be among the most commonly notified diseases preventable by vaccines. In this article, we discuss the vaccines used to prevent these infections, with the aim of expanding knowledge and the practice of prevention of these infectious diseases.Conclusions: Although the vaccines against A and B hepatitis are recommended for various risk groups, estimated vaccine coverage is still modest and many vaccination opportunities are lost. In order to reduce the incidence of A and B hepatitis, which are preventable by vaccines, it is necessary for physicians to encourage their patients to be vaccinated.

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“…[6][7][8][9][10] Vaccination is a proven method for preventing the spread of infection as well as controlling outbreaks, both directly by reducing transmission of the virus, and indirectly by establishing herd immunity. [11][12][13][14][15][16][17][18][19] The impact of herd immunity on levels of symptomatic hepatitis A has been demonstrated in Israel, where the immunization of children has decreased rates of symptomatic disease among adults within a few years. 19 Vaccination programs against hepatitis A are effective; however, they can also be costly when applied to whole populations.…”

Section: Introductionmentioning

confidence: 99%