Active Flow Control Programs at NASA, the U.S.Air Force, and DARPA have been initiated with the goals of obtaining revolutionary advances in aerodynamic performance and maneuvering compared to conventional approaches. These programs envision the use of actuators, sensors, and controllers on applications such as aircraft wings/tails, engine nacelles, internal ducts, nozzles, projectiles, weapons bays, and hydrodynamic vehicles. Anticipated benefits of flow control include reduced weight, part count, and operating cost and reduced fuel burn (and emissions), noise and enhanced safety if the sensors serve a dual role of flow control and health monitoring. To get from the bench-top or laboratory test to adaptive distributed control systems on realistic applications, reliable validated design tools are needed in addition to sub-and large-scale wind-tunnel and flight experiments. This paper will focus on the development of tools for active flow control applications.