Control of follicular development and luteal function in the mare: Effects of a GnRH antagonist

Watson, E.D.; Pedersen, Hanne Gervi; Thomson, Scott; Fraser, Hamish M.

doi:10.1016/s0093-691x(00)00375-7

Cited by 31 publications

(20 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, it was shown that this is the time when circulating concentrations of biologically active dimeric inhibin are increasing, before the first and subsequent ovulations. Furthermore, in previous years in our cyclic pony mares, the largest subordinate follicle did not start to decrease in size until approximately 3 days before ovulation (Pedersen, 2000). This is at a time when circulating concentrations of inhibin A are very high and, therefore, the preovulatory increase in inhibin is temporally associated with regression of the subordinate follicle.…”

Section: Discussionmentioning

confidence: 46%

“…The faster growth rate of the preovulatory follicle at subsequent ovulations compared with the first ovulation has been reported (Ginther, 1990) and is probably due to the higher circulating LH concentrations at subsequent ovulations (Freedman et al, 1979). Circulating LH is thought to be important in the final growth and maturation phase of the follicle in mares (Gastal et al, 2000;Watson et al, 2000).…”

Section: Discussionmentioning

confidence: 99%

“…The antiserum (AFP-2062096) was specific for equine FSH and used at a final dilution of 1:100 000. Otherwise, the method was the same as that described by Watson et al (2000). The main crossreactivity of this antiserum was with equine LH (eLH; 2.5%).…”

Section: Hormone Assaysmentioning

confidence: 99%

“…Plasma oestradiol concentrations were measured as described by Watson et al (2000). Only plasma collected from transitional mares was assayed for oestradiol.…”

Section: Hormone Assaysmentioning

confidence: 99%

See 3 more Smart Citations

Plasma FSH, inhibin A and inhibin isoforms containing pro- and -alphaC during winter anoestrus, spring transition and the breeding season in mares

Watson¹

2002

Reproduction

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 46%

Section: Discussionmentioning

confidence: 99%

Section: Hormone Assaysmentioning

confidence: 99%

“…Plasma oestradiol concentrations were measured as described by Watson et al (2000). Only plasma collected from transitional mares was assayed for oestradiol.…”

Section: Hormone Assaysmentioning

confidence: 99%

See 2 more Smart Citations

Plasma FSH, inhibin A and inhibin isoforms containing pro- and -alphaC during winter anoestrus, spring transition and the breeding season in mares

Watson¹

2002

Reproduction

View full text Add to dashboard Cite

“…The GnRH antagonist, Antarelix, injected (0.1 mg . kg -1 , SC) on day 8 of dioestrus eliminates LH dioestrous pulses and delays ovulation for approximately 9.5 days [33].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the effects of two GnRH antagonists on LH and FSH secretion, follicular growth and ovulation in the mare

2002

View full text Add to dashboard Cite

-The effects of two GnRH antagonists were tested in order to delay and/or synchronise ovulation in mares. Five mares received Antarelix (0.01 mg . kg -1 ), 5 mares received Cetrorelix (the same dose), 5 mares (control mares) received the vehicle intravenously, twice daily, for 8 days from the day the largest follicle reached 22 mm following prostaglandin administration. Ovulation was postponed in all mares injected with Antarelix (19.4 ± 1.2 days after the beginning of the treatment) and in 2/5 mares injected with Cetrorelix (20 ± 1 days) vs. 6.2 ± 0.4 days in control mares. During the treatment, LH concentrations were strongly depressed in Antarelix and in Cetrorelix mares (1.6 ± 0.1 and 3.8 ± 0.5 ng . mL -1 respectively vs. 21 ± 2.5 ng . mL -1 in control mares). In the 3 Cetrorelix mares which ovulated during the treatment, 2 initiated their LH surge at this moment. FSH concentrations were not affected in Antarelix or in Cetrorelix mares during the treatment (11.4 ± 1.3 and 7.9 ± 0.8 ng . mL -1 respectively vs. 10.5 ± 0.8 ng . mL -1 in control mares). In conclusion, Antarelix seems more efficient than Cetrorelix for postponing ovulation in mares. The role of LH in antral follicular development before the preovulatory stage is confirmed. Reprod. Nutr. Dev. 42 (2002) [251][252][253][254][255][256][257][258][259][260][261][262][263][264] 251 mare / GnRH antagonist / ovulation / FSH / LH

show abstract

Effect of Chromium Supplementation on Productive and Reproductive Performances and Some Metabolic Parameters in Late Gestation and Early Lactation of Dairy Cows

Kafilzadeh

Shabankareh

Targhibi

2012

Biol Trace Elem Res

View full text Add to dashboard Cite

The objective of this study was to determine the effect of supplemental chromium as chromium-L-methionine (Cr-Met) on productive and reproductive performances and some metabolic parameters in late gestation and early lactation of dairy cows. Sixty multiparous Holstein dairy cows according to prior lactation, parity, body mass (682±33 kg), and expected calving date were divided equally (30 cows/treatment) and were randomly allocated to one of the two groups. One group received basal diet without Cr (control group) and another group received Cr-Met supplement added at manufacturer's recommended level (8 mg of "Cr"/head per day) from 21 days before expected calving date until 21 days of lactation. Supplemental Cr tended to increase milk yield (P=0.08) while percentage of lactose and lactose yield increased (P<0.01). Chromium supplementation decreased serum nonesterified fatty acids concentration at 7 days prepartum and 21 days postpartum. Serum insulin concentration for cows receiving Cr was higher than the control group (P=0.05). Serum cortisol concentration decreased (P<0.05) in prepartum period in supplemented group. Chromium did not affect concentrations of metabolic parameters at calving. However, serum glucose concentration increased at 21 days postpartum in the supplemented group (P<0.05). Chromium supplementation increased neutrophil and neutrophil to lymphocyte ratio in prepartum period (P<0.05). Based on serum concentrations of progesterone, days to first ovulation tended (P=0.07) to occur earlier in the supplemented group. Furthermore, days to first service and days to first estrus of the supplemented group occurred earlier than the control group (P<0.05) but days open, services per conception and conception rates at first insemination did not differ between two groups (P>0.05). Percentage of cyclic cows at 36 days postpartum and estrous behavior before AI was higher in the supplemented group.

show abstract

Control of follicular development and luteal function in the mare: Effects of a GnRH antagonist

Cited by 31 publications

References 28 publications

Plasma FSH, inhibin A and inhibin isoforms containing pro- and -alphaC during winter anoestrus, spring transition and the breeding season in mares

Plasma FSH, inhibin A and inhibin isoforms containing pro- and -alphaC during winter anoestrus, spring transition and the breeding season in mares

Comparison of the effects of two GnRH antagonists on LH and FSH secretion, follicular growth and ovulation in the mare

Effect of Chromium Supplementation on Productive and Reproductive Performances and Some Metabolic Parameters in Late Gestation and Early Lactation of Dairy Cows

Contact Info

Product

Resources

About