Control of hepatocyte function on collagen foams: sizing matrix pores toward selective induction of 2-D and 3-D cellular morphogenesis

Ranucci, Colette S.; Kumar, Ajay; Batra, Surendra P; Moghe, Prabhas V.

doi:10.1016/s0142-9612(99)00238-0

Cited by 179 publications

(121 citation statements)

References 33 publications

Supporting

Mentioning

117

Contrasting

Order By: Relevance

“…Specific cells require different pore sizes for optimal attachment, growth and motility (Table 2) (Ranucci et al, 2000). A recent study (Yang et al, 2010)on variable pore size collagen gel found that cell migration is hindered by small pore size that invasive distance was not very sensitive in the pore size rang of 5-12µm.…”

Section: Pore Size Of Tissue Engineering Scaffoldmentioning

confidence: 99%

Cell Responses to Surface and Architecture of Tissue Engineering Scaffolds

Chang¹,

Wang²

2011

Regenerative Medicine and Tissue Engineering - Cells and Biomaterials

336

305

View full text Add to dashboard Cite

Section: Pore Size Of Tissue Engineering Scaffoldmentioning

confidence: 99%

Cell Responses to Surface and Architecture of Tissue Engineering Scaffolds

Chang¹,

Wang²

2011

Regenerative Medicine and Tissue Engineering - Cells and Biomaterials

336

305

View full text Add to dashboard Cite

“…Topography of scaffold surface influences spreading characteristics and activity of cells. 107 The existence of grooves may inhibit cell movement to bend its cytoskeleton 108 or reshape its actin filaments to adjust to the new topography. 109 Curtis proposed a term "topographic reaction" to describe that cells react as a response to substratum in microscale through changes in cell orientation, motility and adhesion.…”

Section: © 2 0 0 8 L a N D E S B I O S C I E N C E D O N O T D I S mentioning

confidence: 99%

Cell colonization in degradable 3D porous matrices

Lawrence

Madihally

2008

Cell Adhesion & Migration

178

155

View full text Add to dashboard Cite

Cell colonization is an important in a wide variety of biological processes and applications including vascularization, wound healing, tissue engineering, stem cell differentiation and biosensors. During colonization porous 3D structures are used to support and guide the ingrowth of cells into the matrix. In this review, we summarize our understanding of various factors affecting cell colonization in three-dimensional environment. The structural, biological and degradation properties of the matrix all play key roles during colonization. Further, specific scaffold properties such as porosity, pore size, fiber thickness, topography and scaffold stiffness as well as important cell material interactions such as cell adhesion and mechanotransduction also influence colonization.

show abstract

“…Collagen can be prepared in a number of different forms with different application: shields used in ophthalmology (Rubinstein, 2003;Yoel & Guy, 2008) matrices for burns/wounds (Keck et al, 2009;Wollina et al, 2011), gel formulation in combination with liposomes for sustained drug delivery (Wallace & Rosenblatt, 2003;Weiner et al, 1985;Rao, 1996), as controlling material for transdermal delivery (Rao, 1996;Thacharodi & Rao, 1996), nanoparticles for gene delivery (Minakuchi et al, 2004) and basic matrices for cell culture systems. Therefore thin sheets and gels are substrates for smooth muscle (Dennis et al, 2007;Engler et al, 2004), hepatic (Hansen & Albrecht, 1999;Ranucci et al, 2000), endothelial Deroanne et al, 2001;Titorencu et al, 2010), and epithelial cells (Haga et al, 2005), while matrices are often used to engineer skeletal tissues such as cartilage (Stark et al, 2006;Schulz et al, 2008), tendon (Gonçalves-Neto et al, 2002;Kjaer, 2004) and bone (Guille et al, 2005). It is known that the goal of tissue engineering (TE) is to repair and restore damaged tissue function.…”

Section: Collagen-based Scaffolds For Tissue Engineeringmentioning

confidence: 99%