Control of the Formation and Reaction of Copper-Oxygen Adduct Complexes in Multiphase Streams

The bridge towards a more stable and active side-on-peroxido (Cu2II(µ-η2:η2-O2)) complex as a tyrosinase model system

“…Mimicking the active site of tyrosinase by designing and synthesizing small structural analogues, provides the possibility to reveal the mechanism and transfer the enzyme's catalytic activity outside of its biological application, towards a synthetic catalytic system. Aer the rst catalytically active tyrosinase model system was reported by Regliér et al, 9 further systems were developed by the groups of, for example, Bulkowski et al, 10 Casella et al, [11][12][13] Stack et al, 14 Lumb and Ottenwaelder et al, [15][16][17][18][19] Tuczek et al [20][21][22][23][24][25][26][27][28] and Herres-Pawlis et al [29][30][31][32][33][34][35][36] (Fig. 1).…”