Controle de crianças e adolescentes comunicantes de tuberculosos, Rio de Janeiro, RJ

Caldeira, Zelina M R; Sant’Anna, Clemax Couto; Aidé, Miguel Abdom

doi:10.1590/s0034-89102004000300001

Cited by 22 publications

(18 citation statements)

References 7 publications

(4 reference statements)

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“…Age group was predominantly >10 years and adults, which is similar to a study conducted in São José do Rio Preto-SP (9) . Data of the MS (3) show that in Brazil, the disease is most frequently detected in the 25 to 35 age group and there is low incidence in the <10 year age group, although this group is generally more exposed due to the proximity and intensity of contact with the index case (9,14) . Average residents per home in Pelotas-Brazil were 2.9 (12) .…”

Section: Discussionmentioning

confidence: 99%

“…This result was attributed to factors such as reduced time availability of home contacts and distance between the residence and the TB clinic. This finding can also be attributed to the fact that contacts do not undergo diagnostic testing requested by the PCT, which was especially detected in the productive age group (14) . A total of 21% underwent the bacilloscopy, 23.7% had chest x-rays and only 5.3% had both tests when requested jointly.…”

Section: Discussionmentioning

confidence: 99%

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O programa de controle da tuberculose em Pelotas/RS, Brasil: investigação de contatos intradomiciliares

Lima

Schwartz²,

Gonzáles³

et al. 2013

Rev. Gaúcha Enferm.

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The aim of this study is to evaluate the investigation actions of home contacts of tuberculosis (TB) index cases in the Tuberculosis Control Program (TCP) of Pelotas/RS -Brazil. This cross-sectional descriptive study was based on data from the records of index cases. The sample consisted of 163 contacts of 68 subjects with pulmonary TB in treatment in the TCP between June and August, 2009. These contacts were predominantly female, over 10 years of age and the daughters of index cases. The requested examination was a chest radiography and bacilloscopy. Active TB was found in 1.8 % of contacts. Results show that assistance for TB patients in Pelotas-Brazil, which is centralized in a single specialized service, hinders the investigation of home contacts. Primary care is required to narrow the gap between professionals and the family, and facilitate early diagnosis and interruption of the TB transmission chain in a timely manner.Descriptors: Contact tracing. Tuberculosis. Health services evaluation. RESUMO Objetivou-se avaliar as ações de investigação dos contatos intradomiciliares dos casos índices de tuberculose (TB) no Programa de Controle da Tuberculose (PCT), de Pelotas/RS -

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

O programa de controle da tuberculose em Pelotas/RS, Brasil: investigação de contatos intradomiciliares

Lima

Schwartz²,

Gonzáles³

et al. 2013

Rev. Gaúcha Enferm.

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“…(7) In our study, we observed that 35 children (38%) whose contacts presented positive sputum smear results also presented positive tuberculin skin test results and, among the unexposed, only 18% presented the same results, demonstrating that these children in contact with adult patients with active TB were 2.8 times more likely to be infected with M. tuberculosis than were those who were contacts of adults with negative sputum smear microscopy. In a study carried out in Rio de Janeiro, (16) of the 181 children submitted to the tuberculin skin test, a strong reaction was observed in 110 contacts (59.8%), and a ≥ 15 mm reaction was detected in 66 children (35.9%). It should be noted that the diagnosis of latent infection with M. tuberculosis through the tuberculin skin test in children is greatly affected by the BCG vaccination or by the exposure to environmental mycobacteria, which affects its specificity.…”

Section: Discussionmentioning

confidence: 99%

“…Although the new NMH guidelines define as positive only a ≥ 15 mm reaction in individuals vaccinated within the last two years and a > 10 mm reaction in those vaccinated more than two years before, there is no consensus on these interpretations in the literature. (10,(16)(17)(18) In order to avoid the low specificity of the tuberculin skin test, two new commercial tests, based on IFN-γ expression-Interferon Gamma Release Assays (IGRAs)-synthesized by lymphocytes in response to specific anti- early prevention or identification of TB cases. In addition, in order to institute chemoprophylaxis in this age bracket, it is essential that investigations be conducted in young individuals in contact with patients with positive or negative sputum smear microscopy.…”

Section: Discussionmentioning

confidence: 99%

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Comunicantes domiciliares jovens de pacientes com TB pulmonar na região da grande Vitória (ES): um estudo de coorte

et al. 2009

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Objective: To compare clinical, radiological and laboratory aspects of household contacts, aged 15 or younger, of patients presenting a positive culture for Mycobacterium tuberculosis. Methods: This was a cohort study comparing children and adolescents (≤ 15 years of age) who were household contacts of TB cases presenting positive sputum smear and positive culture results (exposed group, n = 100) or negative sputum smear and positive culture results (unexposed group, n = 55). All of the contacts were evaluated via the TB control program of a university hospital in the city of Vitória, Brazil, between July of 2003 and December of 2006. Results: Of the 155 minors evaluated, 87 (56.1%) were female and 68 (43.9%) were male. Of those 155, 28 (18%) were aged 5 or younger, 62 (40%) were aged 5-9, and 65 (42%) were aged 10-15. Symptoms of the disease were found in 17 (17%) of the 100 contacts in the exposed group and in 9 (16%) of the 55 in the unexposed group (p = 0.86). Chest X-rays showed alterations in 20 (21%) and 2 (4%) of the contacts in the exposed and unexposed groups, respectively (RR = 6.9; p = 0.004). In the exposed and unexposed groups, respectively, 35 (38%) and 10 (18%) of the contacts presented positive results on the tuberculin skin test (RR = 2.8; p = 0.01). Of the 100 contacts in the exposed group, 5 (5%) were diagnosed with TB, which was not diagnosed in any of those in the unexposed group (p = 0.08). Conclusions: Although no significant difference was found between the two groups regarding the incidence of TB, it is of note that there is a greater risk of becoming infected with M. tuberculosis if the bacterial load of the index case is high.Keywords: Tuberculosis; Mycobacterium tuberculosis; Tuberculosis, pulmonary; Child; Adolescent. ResumoObjetivo: Comparar aspectos clínicos, radiológicos e laboratoriais de contatos domiciliares, menores de 15 anos, de pacientes com cultura positiva para Mycobacterium tuberculosis. Métodos: Realizou-se um estudo de coorte comparando crianças e adolescentes (≤ 15 anos) que eram contatos domiciliares de casos de TB com baciloscopia e cultura positiva (grupo exposto, n = 100) ou com baciloscopia negativa e cultura positiva (grupo não-exposto, n = 55). Todos os contatos foram avaliados no período de julho de 2003 a dezembro de 2006, no programa de controle da TB de um hospital universitário na cidade de Vitória (ES). Resultados: Das 155 contatos avaliados, 87 (56,1%) eram do sexo feminino e 68 (43,9%) do masculino. Do total, 28 (18%) eram menores de 5 anos; 62 (40%), entre 5-9 anos; e 65 (42%), entre 10-15 anos. Foi detectada a presença de sintomas de TB em 17 (17%) dos 100 contatos no grupo exposto e em 9 (16%) dos 55 no grupo não-exposto (p = 0,86). A radiografia de tórax apresentou alterações em 20 (21%) e 2 (4%) dos contatos nos grupos exposto e não-exposto, respectivamente (RR = 6,9; p = 0,004). Nos grupos exposto e não-exposto, respectivamente, 35 (38%) e 10 (18%) dos contatos apresentaram prova tuberculínica positiva (RR = 2,8; p = 0,01). No total, 5 co...

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Tuberculosis contact tracing among children and adolescent referred to children's hospital in Rio de Janeiro, Brazil

Mendonça

Kritski

Sant’Anna

2015

The Brazilian Journal of Infectious Diseases

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Controle de crianças e adolescentes comunicantes de tuberculosos, Rio de Janeiro, RJ

Abstract: Objective To detect tuberculosis (TB) disease or infection among contacts of pulmonary

Cited by 22 publications

References 7 publications

O programa de controle da tuberculose em Pelotas/RS, Brasil: investigação de contatos intradomiciliares

O programa de controle da tuberculose em Pelotas/RS, Brasil: investigação de contatos intradomiciliares

Comunicantes domiciliares jovens de pacientes com TB pulmonar na região da grande Vitória (ES): um estudo de coorte

Tuberculosis contact tracing among children and adolescent referred to children's hospital in Rio de Janeiro, Brazil

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