In this work, we address the existence of insensitizing controls for a coupled system of fourth-and second-order parabolic equations known as the stabilized Kuramoto-Sivashinsky model. The main idea is to look for control functions such that some functional of the state is locally insensitive to the perturbations of initial data. Let O be a nonempty observation set for the solution component(s) w.r.t. the L 2 -norm(s) and ω be another nonempty set where the interior controls are acting. Then, we study the associated insensitizing control problem under the assumption O ∩ ω = ∅ and as usual, it can be shown that this is equivalent to a null-controllability problem for a cascade system where the number of equations are doubled. This new problem is studied by means of the classical duality arguments and Carleman estimates, but unlike other insensitizing problems for scalar systems, the election of the Carleman tools depends on the number of components of the system to be insensitized.