Controllable biosynthesis of gold nanoparticles from a Eucommia ulmoides bark aqueous extract

Guo, Mingxia; Li, Wei; Yang, Feng; Liu, Huihong

doi:10.1016/j.saa.2015.01.109

Cited by 101 publications

(27 citation statements)

References 38 publications

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“…The average diameter of oligonucleotide-functionalized AuNPs was shown to be 65.5 nm in size [35], and the average size of AuNPs was 18.2 nm [36]. The average zeta potential value for AuNPs was found to be −21.3 mV [36], and the negative potential of AuNPs due to the presence of bioorganic components as a capping agent was reported.…”

Section: Discussionmentioning

confidence: 92%

“…The average zeta potential value for AuNPs was found to be −21.3 mV [36], and the negative potential of AuNPs due to the presence of bioorganic components as a capping agent was reported. The stability of AuNPs increases from −22.3 to −65.0 mV, while pH increases from 6 to 12, and we also found that AuNPs were more stable at pH 12 [37].…”

Section: Discussionmentioning

confidence: 97%

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Gold nanoparticle induces mitochondria-mediated apoptosis and cell cycle arrest in nonsmall cell lung cancer cells

et al. 2017

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The present study reports the chemical synthesis of gold nanoparticles (AuNPs) using sodium borohydride as a reducing and capping agent. The various temperatures and time intervals were investigated for controlled formation of AuNPs. The characterization of AuNPs was studied using UV-vis spectrophotometer, transmission electron microscope (TEM), selected area diffraction (SAED), energy-dispersive X-ray spectrophotometer (Edx), dynamic light scattering (DLS), zeta potential, and X-ray powder diffraction (XRD), and results indicated that AuNPs were spheroid in shape and cubic lattice and face centered in nature with 29 nm in size. AuNPs have potential antimicrobial activity against selected human clinical pathogens. IC 50 concentration of AuNPs was determined as 20 μg/ml against non-small cell lung cancer (NSCLC) cell lines using MTT assay. The morphological and apoptosis effects of AuNPs on NSCLC were investigated using acridine orange/ethidium bromide (AO/EB), 2′,7′-dichlorofluorescein-diacetate (DCFH-DA), rhodamine 123, and 4′,6-diamidino-2-phenylindole (DAPI) staining method, and results indicated that AuNPs have potential anticancer activity against NSCLC cell lines. The anticancer activity of AuNPs is that it has less toxicity against human HBL100 normal cells. These anticancer potentials of AuNPs were compared with the standard drug cisplatin. Moreover, after 24 h exposure, AuNPs arrest the cell cycle at G2/M phase in A549 cells. These findings suggested that AuNPs could act as a potential anticancer agent against lung cancer.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 97%

Gold nanoparticle induces mitochondria-mediated apoptosis and cell cycle arrest in nonsmall cell lung cancer cells

et al. 2017

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“… Cassia fistula Fabaceae Golden rain tre FTIR, UV−650 spectrophotometer, FTIR, SEM 55.2–98.4 – [87] 2. Eucommia ulmoides Eucommiaceae Hardy rubber tree UV–Visible spectroscopy, HRTEM, EDX, XRD, RA-FTIR 16.4 Spherical [88] 3. Acacia nilotica Fabaceae Prickly acacia UV–vis, FT-IR, XRD, TEM, 10–50 Quasi-spherical [89] 4.…”

Section: Different Parts Of Plantmentioning

confidence: 99%

Phyto-assisted synthesis, characterization and applications of gold nanoparticles – A review

Santhoshkumar

Rajeshkumar

Kumar

2017

Biochemistry and Biophysics Reports

164

125

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Nanotechnology is the formation, running and use of operation at the nanomaterial size scale (1–100 nm). Nanoscale materials can also be obtained by biological synthesis materials via eco-friendly green chemistry based technique. Current development and numerous strategies involved in the green synthesis of nanoparticles were focussed. This review mainly focused on plants which include scientific name, family name, common name, plant parts, its characterization, size and shape of the nanoparticles. Plant extract which was done experimentally gives its various characterization which leads to the identification of compounds of different nano size and shape. Biosynthesis of gold nanoparticles is in different shapes like spherical, rod, cubic, triangle and also in different sizes. Various application and importance of gold nanoparticles in numerous fields were discussed. The mark of the review is to provide an overview of recent learning in biosynthesized nanoparticles, its characterization and their potential applications.

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“…Hence, it is very imperative to develop an alternate synthetic route by greener method, which is eco‐friendly and at the same time cost‐effective. Greener synthesis of nanoparticles by biological methods using microorganisms like bacteria, fungi, algae and plant extracts such as Chenopodium murale , Erythrina indica lam, Eucalyptus chapmaniana , Eucommia ulmoides , Pogestemon benghalensis , ipomoea, mango peel, Hovenia dulcis , Phoenix dactylifera L, and Croton Caudatus Geisel were reported.…”

Section: Introductionmentioning

confidence: 99%

Green biosynthesis of gold nanoparticles using Croton sparsiflorus leaves extract and evaluation of UV protection, antibacterial and anticancer applications

Boomi

Poorani²,

Selvam

et al. 2020

Applied Organom Chemis

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Our study reports greener synthesis of gold nanoparticles (AuNPs) tethered to the extract of Croton sparsiflorus and in vitro evaluation of UV‐protection, antibacterial and anticancer activities. Sophisticated instrumental analytical techniques such as UV–vis spectrophotometer, FT‐IR, XRD, FE‐SEM, and TEM were employed for the existence and confirmation of the nanoparticles. FT‐IR and HPLC analysis were executed in the identification of the plausible functional groups implicated in the reduction of gold ions to AuNPs. UV protection property and antibacterial action of AuNPs‐coated cotton fabric were also presented. Moreover, in vitro anticancer evaluation against HepG2 cell line was conducted by MTT assay for Croton sparsiflorus extract derived AuNPs in different concentrations (50 to 150 μg/ml). Thus, the results of this work revealed that greener synthesized AuNPs exhibited good therapeutic applications as UV‐protection, antibacterial and anticancer agents.

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Controllable biosynthesis of gold nanoparticles from a Eucommia ulmoides bark aqueous extract

Cited by 101 publications

References 38 publications

Gold nanoparticle induces mitochondria-mediated apoptosis and cell cycle arrest in nonsmall cell lung cancer cells

Gold nanoparticle induces mitochondria-mediated apoptosis and cell cycle arrest in nonsmall cell lung cancer cells

Phyto-assisted synthesis, characterization and applications of gold nanoparticles – A review

Green biosynthesis of gold nanoparticles using Croton sparsiflorus leaves extract and evaluation of UV protection, antibacterial and anticancer applications

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