Controlled Drug Delivery Systems: Concepts and Rationale

Abstract

Modern pharmaceutical research and development has evolved to rely heavily on controlled drug delivery systems because they provide creative ways to improve therapeutic results while reducing side effects. The underlying ideas and justification for controlled drug delivery systems are covered in detail in this chapter. Beginning with a discussion of the drawbacks of conventional drug delivery techniques and the benefits of controlled release, the chapter explains the need for controlled drug delivery systems in modern medicine. The requirements for the design and formulation of controlled drug delivery systems have also been discussed in the chapter. The concepts of controlled drug release, which cover a variety of mechanisms, including diffusion, erosion, and osmosis, take up a sizeable section of the chapter. Additionally, emphasis is put on the function that mathematical modeling plays in predicting and optimizing drug release characteristics. It examines the wide spectrum of therapeutic uses for controlled drug administration, such as the treatment of chronic pain, cancer, diabetes, and other chronic disorders. The chapter also illuminates the future trends of such drug delivery systems like nanotechnology, personalized medicines, and advancements in medical devices. It also explores regulatory aspects and challenges involved in the design and commercialization of these systems, placing emphasis on the necessity of stringent quality control and safety evaluations. In conclusion, this chapter is a useful resource for researchers, scientists, and medical experts who want to understand underlying ideas and justifications of controlled drug delivery systems.