Controlled helical senses of twisting in two-, three- and four-layer cyclophanes with planar chirality

Abstract

We synthesized planar chiral cyclophanes with multiple pairs of helical conformations that were generated by twisting at the interlayer. Three- and four-layer cyclophanes preferred a homochiral form with a single...

Study of optical rotation based on the molecular structure in fused oligomers of macrocycles

“…Such conformational interinuence could be a driving force for a molecule to predominantly adopt a particular conformation among multiple conformations. 14,15 It should be noted that conformational interinuence can lead to a homochiral situation and sometimes a specic heterochiral situation (Scheme 1b, controlled). If each macrocyclic element has no preference for a particular sense of twisting and no interinuence could work between elements, multiple conformers with an identical and different sense of twisting would be statistically populated in the solution (Scheme 1b, less controlled).…”