“…70 Proposed benefits include 1) reduced intraoperative blood loss, 2) improved surgical visualization, 3) shortened operative time, and 4) decreased use of and exposure to blood products. 43 The efficacy and safety of this technique have been studied in general plastic surgery, 18,19,23,36,43,72 neurosurgery, 1,3,24,25,28,31,47,48,57,62,74 maxillofacial surgery, 4,7,16,20,21,38,51,54,59,60,73 orthopedic surgery, 2,6,17,35,41,44,46,52,53,67,69 general surgery, 15,33,65 otolaryngology, 8,29,55,56,61,71 bur...…”