Controlled release of curcumin from coaxial electrospun nanofiber mats

Kim, Huiseon; Bae, Ju Eun; Shin, Min Jae

doi:10.1002/bkcs.12575

Cited by 3 publications

(1 citation statement)

References 30 publications

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“…Spontaneous adsorption of biomolecules on engineered nanomaterials (ENMs) in biological fluids is an important issue in the field of nanomedicine such as drug delivery systems 1,2 as the adsorbed biomolecules, which are often referred to as biomolecular coronas, alter the biological identity of ENMs. [3][4][5] Due to this, extensive research has been carried out to understand the biomolecular coronas, in particular protein coronas, and their influences on the efficacy of ENMs and related biological processes.…”

Section: Introductionmentioning

confidence: 99%

Probing emergence of biomolecular coronas around drug‐loaded liposomal nanoparticles in the solution by using nanoparticle tracking analysis

Jeong

Joung

Jang

et al. 2023

Bulletin Korean Chem Soc

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Various state‐of‐art analytical methods have played a critical role in understanding the nature of protein coronas. In most cases, the analyses require the biomolecule‐coated engineered nanomaterials (ENMs) to be isolated from the biological environment by energetic processes. This only allows investigation of so‐called “hard” coronas, which are biomolecules tightly bound to the surfaces of ENMs. We examined fluorescence‐nanoparticle tracking analysis (F‐NTA) as a suitable method to study the formation of natural biomolecular coronas in solution, that is, without separation. The formation of coronas of high‐density lipoprotein, immunoglobulin G, and human serum albumin, and also that of the blood serum around fluorescently labeled PEGylated doxorubicin‐loaded liposomes were investigated in terms of the changes in hydrodynamic size as a function of concentration, incubation time, and PEGylation density of liposomes. From the results, this study successfully demonstrates that NTA in the fluorescence mode is indeed suitable to probing intact biomolecular coronas in the native environment.

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Section: Introductionmentioning

confidence: 99%

Probing emergence of biomolecular coronas around drug‐loaded liposomal nanoparticles in the solution by using nanoparticle tracking analysis

Jeong

Joung

Jang

et al. 2023

Bulletin Korean Chem Soc

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Controlled Mesoscopic Growth of Polymeric Fibers Using Liquid Crystal Template

Han

Kim

Lee

et al. 2023

Macromol. Rapid Commun.

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Orientation‐controlled polymeric fiber is one of the most exciting research topics to rationalize the multifunctionality for various applications. In order to realize this goal, the growth of polymeric fibers should be controlled using various techniques like extrusion, molding, drawing, and self‐assembly. Among the various candidates to fabricate the orientation‐controlled polymeric fibers, the template‐assisted assembly guided by a liquid crystal (LC) matrix is the most promising because the template can be manipulated easily with various methods like surface anchoring, rubbing, geometric confinement, and electric field. This review introduces the recent progress toward the directed growth of polymeric fibers using the LC template. Three representative LC‐templated polymerization techniques to fabricate fibers include chemical or physical polymerization from the monomers mixed in LC matrix, patterned fibers formed from LC‐templated reactive mesogens, and orientation‐controlled nanofibers by infiltrating vaporized monomers between LC molecules. The orientation‐controlled polymeric fibers will be used in electro‐optical switching tools, tunable hydrophilic or hydrophobic surfaces, and control of phosphorescence, which can open a way to design, fabricate, and modulate nano‐ to micron‐scale fibers with various functions on demand.

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Non-Toxic Natural Additives to Improve the Electrical Conductivity and Viscosity of Polycaprolactone for Melt Electrospinning

Kim

Park²,

Park

et al. 2023

Applied Sciences

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Polycaprolactone (PCL) is biodegradable and non-toxic, making it an eco-friendly polymer with various medical applications. In order to increase the stability of PCL used in the field of medical applications, it is necessary to be able to produce fibers with a melt electrospinning method that does not use toxic hydrophobic solvents. However, PCL has very high viscosity and low conductivity, making melt electrospinning difficult. This study presents natural additives enabling the solvent-free melt electrospinning of PCL, wherein the physical properties (i.e., conductivity and viscosity) of the additive-mixed PCL are analyzed. Among the natural additives added to PCL, 7 wt% gallic acid increased conductivity by 81 times and decreased viscosity by 1/8526 times, showing the best results. We believe that our study, improving the physical properties of melt PCL by adding natural additives, will be of great help to the development of the melt electrospinning method of PCL.

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Controlled release of curcumin from coaxial electrospun nanofiber mats

Cited by 3 publications

References 30 publications

Probing emergence of biomolecular coronas around drug‐loaded liposomal nanoparticles in the solution by using nanoparticle tracking analysis

Probing emergence of biomolecular coronas around drug‐loaded liposomal nanoparticles in the solution by using nanoparticle tracking analysis

Controlled Mesoscopic Growth of Polymeric Fibers Using Liquid Crystal Template

Non-Toxic Natural Additives to Improve the Electrical Conductivity and Viscosity of Polycaprolactone for Melt Electrospinning

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