Controlled Rod Nanostructured Assembly of Diphenylalanine and Their Optical Waveguide Properties

Li, Qi; Jia, Yi; Dai, Luru; Yang, Yang; Li, Junbai

doi:10.1021/acsnano.5b00623

Cited by 219 publications

(203 citation statements)

References 39 publications

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“…Figure 1f shows uniform FF peptide microrod arrays grown on a 1.25 × 1.25 cm 2 gold-coated silicon substrate. Since FF peptide microrods are a good optical waveguide axially but poor light transmitter radially29, the visibility of the yellow gold film provides an easy way to confirm the good vertical alignment of the microrod arrays (Fig. 1f and Supplementary Fig.…”

Section: Resultsmentioning

confidence: 99%

Self-assembly of diphenylalanine peptide with controlled polarization for power generation

et al. 2016

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Peptides have attracted considerable attention due to their biocompatibility, functional molecular recognition and unique biological and electronic properties. The strong piezoelectricity in diphenylalanine peptide expands its technological potential as a smart material. However, its random and unswitchable polarization has been the roadblock to fulfilling its potential and hence the demonstration of a piezoelectric device remains lacking. Here we show the control of polarization with an electric field applied during the peptide self-assembly process. Uniform polarization is obtained in two opposite directions with an effective piezoelectric constant d33 reaching 17.9 pm V−1. We demonstrate the power generation with a peptide-based power generator that produces an open-circuit voltage of 1.4 V and a power density of 3.3 nW cm−2. Devices enabled by peptides with controlled piezoelectricity provide a renewable and biocompatible energy source for biomedical applications and open up a portal to the next generation of multi-functional electronics compatible with human tissue.

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Section: Resultsmentioning

confidence: 99%

Self-assembly of diphenylalanine peptide with controlled polarization for power generation

et al. 2016

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“…FF incidentally is also the core recognition motif of the β-amyloid polypeptide, a peptide associated with Alzheimer’s disease 1 . It can self-assemble into a variety of structures like microtubes, nanotubes 2 , microcrystals, nanofibers 3 , nanorods 4, 5 and nanowires 6 .…”

Section: Introductionmentioning

confidence: 99%

Modulation of Peptide Based Nano-Assemblies with Electric and Magnetic Fields

Pandey

Saikia

Sasidharan

et al. 2017

Sci Rep

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Peptide based nano-assemblies with their self-organizing ability has shown lot of promise due to their high degree of thermal and chemical stability, for biomaterial fabrication. Developing an effective way to control the organization of these structures is important for fabricating application-oriented materials at the molecular level. The present study reports the impact of electric and magnetic field-mediated perturbation of the self-assembly phenomenon, upon the chemical and structural properties of diphenylalanine assembly. Our studies show that, electric field effectively arrests aggregation and self-assembly formation, while the molecule is allowed to anneal in the presence of applied electric fields of varying magnitudes, both AC and DC. The electric field exposure also modulated the morphology of the self-assembled structures without affecting the overall chemical constitution of the material. Our results on the modulatory effect of the electric field are in good agreement with theoretical studies based on molecular dynamics reported earlier on amyloid forming molecular systems. Furthermore, we demonstrate that the self-assemblies formed post electric-field exposure, showed difference in their crystal habit. Modulation of nano-level architecture of peptide based model systems with external stimulus, points to a potentially rewarding strategy to re-work proven nano-materials to expand their application spectrum.

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“…Diphenylalanine nanotubes exhibit unique functional properties such as crystallinity, high aspect ratios and high thermal stability, and their applications include drug delivery, sensing, and nanoelectronics . Several groups have demonstrated the rich polymorphism of self‐assembled diphenylalanine and their ability to form nanotubes, nanofibrils, nanospheres, and hydrogels …”

Section: Introductionmentioning

confidence: 99%

Polarized raman spectroscopy for determining the orientation of di‐d‐phenylalanine molecules in a nanotube

Sereda

Ralbovsky

Vasudev

et al. 2016

J Raman Spectroscopy

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Self-assembly of short peptides into nanostructures has become an important strategy for the bottom-up fabrication of nanomaterials. Significant interest to such peptide-based building blocks is due to the opportunity to control the structure and properties of well-structured nanotubes, nanofibrils, and hydrogels. X-ray crystallography and solution NMR, two major tools of structural biology, have significant limitations when applied to peptide nanotubes because of their non-crystalline structure and large weight. Polarized Raman spectroscopy was utilized for structural characterization of well-aligned D-Diphenylalanine nanotubes. The orientation of selected chemical groups relative to the main axis of the nanotube was determined. Specifically, the C-N bond of CNH3+groups is oriented parallel to the nanotube axis, the peptides’ carbonyl groups are tilted at approximately 54° from the axis and the COO− groups run perpendicular to the axis. The determined orientation of chemical groups allowed the understanding of the orientation of D-diphenylalanine molecule that is consistent with its equilibrium conformation. The obtained data indicate that there is only one orientation of D-diphenylalanine molecules with respect to the nanotube main axis.

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Controlled Rod Nanostructured Assembly of Diphenylalanine and Their Optical Waveguide Properties

Cited by 219 publications

References 39 publications

Self-assembly of diphenylalanine peptide with controlled polarization for power generation

Self-assembly of diphenylalanine peptide with controlled polarization for power generation

Modulation of Peptide Based Nano-Assemblies with Electric and Magnetic Fields

Polarized raman spectroscopy for determining the orientation of di‐d‐phenylalanine molecules in a nanotube

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