Controlled synthesis of low polydispersity Ag@SiO2 core–shell nanoparticles for use in plasmonic applications

Rainville, Luc; Dorais, M.; Boudreau, Denis

doi:10.1039/c3ra41677a

Cited by 55 publications

(43 citation statements)

References 48 publications

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“…[5][6][7][8] Hollow polymeric particles, known as capsules, have been made using the layer-by-layer (LbL) technique. [20][21][22][23][24] TA belongs to a group of hydrolysable tannins and contains digalloyl ester groups connected to a glucose core which has been shown to be versatile for a variety of industrial 25,26 and food applications. [11][12][13] The multilayer capsules comprise ultrathin multilayer shells (<50 nm) and subor micrometer size cavities used for loading and delivery of functional cargo.…”

Section: Introductionmentioning

confidence: 99%

Encapsulation of anticancer drug by hydrogen-bonded multilayers of tannic acid

et al. 2014

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Tannic acid (TA)-based multilayer assemblies have attracted increasing interest for biomedical applications. Here we explore properties of TA-poly(N-vinylpyrrolidone) (TA-PVPON) hydrogen-bonded multilayers for drug encapsulation and long-term storage. We demonstrate that the small molecular weight anticancer drug, doxorubicin (DOX), can be successfully loaded into (TA-PVPON) capsules with high encapsulation efficiency. We have also found that the encapsulated DOX can be efficiently stored inside the capsules for the pH range from pH = 7.4 to pH = 5. We show that the chemical and functional stability of TA at neutral and basic pH values is achieved through complexation with PVPON. The UV-vis spectrophotometry and in situ ellipsometry analyses of the hydrogen bonding interactions between TA and PVPON at different pH values reveal pH-dependent behavior of TA-PVPON capsules for the pH range from pH = 7.4 to pH = 5. Increasing deposition pH value from pH = 5 to pH = 7.4 leads to a 2-fold decrease in capsule thickness. However, this trend is reversed when salt concentration of the deposition solutions is increased from 0.01 M to 0.1 M NaCl. We have also demonstrated that the permeability of (TA-PVPON) capsules prepared using low salt deposition conditions and pH = 7.4 can be increased 2-fold by exposure of the capsules to 0.1 M NaCl salt solutions at the same pH. Our work opens new perspectives for design of novel polymer carriers for controlled drug delivery in cancer therapy.

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Section: Introductionmentioning

confidence: 99%

Encapsulation of anticancer drug by hydrogen-bonded multilayers of tannic acid

et al. 2014

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“…By controlling the pH during the nucleation stage, one can prepare spherical silver NPs free of undesirable rod-like particles ( Figure 3(b)) [48]. In similar conditions involving tannic acid as the reducing agent, lower polydispersity silver cores up to 118 nm in diameter have been obtained [49]. Borohydride reduction has also been used for the production of small noble metal NPs in aqueous media [50] and, notably, of small uniform Au NPs as seeds for the growth of larger spheres, nanorods, and nanoprisms [51].…”

Section: Synthesis Of Metal Coresmentioning

confidence: 96%

Metal-Enhanced Fluorescence and FRET in Multilayer Core-Shell Nanoparticles

Asselin

Viger

Boudreau

2014

Advances in Chemistry

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In recent years, various methods for the synthesis of fluorescent core-shell nanostructures were developed, optimized, and studied thoroughly in our research group. Metallic cores exhibiting plasmonic properties in the UV and visible regions of the electromagnetic spectrum were used to increase substantially the brightness and stability of organic fluorophores encapsulated in silica shells. Furthermore, the efficiency and range of Förster resonant energy transfer (FRET) between donor and acceptor molecules located in the vicinity of the metallic core was shown to be enhanced. Such multilayer nanoparticle architectures offer, in addition to the aforementioned advantages, excellent chemical and physical stability, solubility in aqueous media, low toxicity, and high detectability. In view of these enviable characteristics, a plethora of applications have been envisioned in biology, analytical chemistry, and medical diagnostics. In this paper, advances in the development of multilayer core-shell luminescent nanoparticle structures and selected applications to bioanalytical chemistry will be described.

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“…As a result, a tremendous effort has been made to explore visible lightdriven photocatalysts. Recently, nano-scale noble metals have received intense attention because of their localized surface plasmon resonance (LSPR) [6][7][8][9]. This is much favorable for the full use of sunlight and this kind of material is named as plasmonic photocatalyst.…”

Section: Introductionmentioning

confidence: 99%